| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABZ2023-100 | 2 weeks | 100 µL | $499.00 |
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| ABZ2023-20 | 2 weeks | 20 µL | $149.00 |
Product Overview | |
| Name | BRAT1 Rabbit mAb |
|---|---|
| Accession (Primary) | Q6PJG6 |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Isotype | IgG |
| Species Reactivity | |
| Reacts With | Human |
| Calculated MW | |
| Calculated MW: 88 kDa; Observed MW: 88 kDa | |
| Buffer System | |
| Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. | |
| Storage | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |
| Recommended Dilution | |
| WB-1:1000-1:5000; ICC/IF-1:100-1:200; FC-1:10-1:100; IP-1:20-1:50 | |
| Purification | |
| Affinity Purified | |
| Conjugation | |
| Unconjugated | |
| Modification | |
| Unmodified | |
| Form | |
| Liquid | |
| Background | |
| Involved in DNA damage response; activates kinases ATM, SMC1A and PRKDC by modulating their phosphorylation status following ionizing radiation (IR) stress (PubMed:16452482, PubMed:22977523). Plays a role in regulating mitochondrial function and cell proliferation (PubMed:25070371). Required for protein stability of MTOR and MTOR-related proteins, and cell cycle progress by growth factors (PubMed:25657994). | |
Target Information: ( Q6PJG6 ) | |
| Name | BRAT1 |
| Gene ID | 221927 |
| Other Names | |
| BAAT1; C7orf27; BRCA1-associated ATM activator 1; BRCA1-associated protein required for ATM activation protein 1 | |
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ADMEbio Team
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ADMEbio Team