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CD14 Mouse, Sf9

CD14 Mouse Recombinant, Sf9

 
Catalog #
CDA0010
Uniprot Id
P10810
 
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 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
CDA0010-2 2 µg $120.00
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CDA0010-10 10 µg $290.00
CDA0010-1 1 mg $8,320.00
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Product Overview

NameCD14 Mouse, Sf9
Description
CD14 Mouse Recombinant, Sf9
Accession (Primary)P10810
Immunogen
Anti-human CD14 mAb, clone PAT87H7AT, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human CD14 protein 20-349 amino acids purified from E. coli.
Synonyms
Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein.
Introduction
CD14 (also known lipopolysaccharide (LPS) receptor) is expressed strongly on monocytes and macrophage and weakly on the surface of neutrophils. CD14 is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a high affinity receptor for complexes of LPS and LPS binding protein (LBP). Soluble CD14, also binding to LPS, acts at physiological concentration as an LPS agonist and has, at higher concentrations, an LPS antagonizing effect in cell activation. CD14 has been shown to bind apoptotic cells.
Physical Appearance
Sterile filtered colorless solution.
Formulation
1mg/ml containing PBS, pH-7.4, 10% Glycerol and 0.02% Sodium Azide.
Applications
The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:100.
Type
Mouse Anti Human Monoclonal.
Clone
PAT87H7AT.
Ig Subclass
Mouse IgG 2b heavy chain and k light chain.
Purification Method
CD14 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Storage Procedures
For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.
Stability / Shelf Life
12 months at -20°C. 1 month at 4°C.
Precautions
CD14 Mouse, Sf9 is for research use only and not for use in diagnostic or therapeutic procedures.

Target Information: ( P10810 )

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