| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| CDA0067-2 | 7 days | 2 µg | $120.00 |
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| CDA0067-10 | 7 days | 10 µg | $290.00 | |||
| CDA0067-1 | 7 days | 1 mg | $8,320.00 |
Product Overview | |
| Name | CD3e Human |
|---|---|
| Description | |
| CD3e Human Recombinant | |
| Accession (Primary) | P07766 |
| Synonyms | |
| T-cell surface glycoprotein CD3 gamma chain, CD3-GAMMA, T3G, CD3G. | |
| Introduction | |
| CD3-gamma polypeptide is encoded by CD3 Gamma (CD3G) which together with CD3-epsilon, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, configures the T-cell receptor-CD3 complex. The T-cell receptor-CD3 complex takes part in coupling antigen recognition to numerous intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. Deficiencies in this gene are associated with T cell immunodeficiency. | |
| Source | |
| E.coli. | |
| Physical Appearance | |
| Sterile Filtered colorless solution. | |
| Formulation | |
| CD3G protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.4M urea and 10% glycerol. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 90% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| MGSSHHHHHH SSGLVPRGSH MGS QSIKGNH LVKVYDYQED GSVLLTCDAE AKNITWFKDG KMIGFLTEDK KKWNLGSNAK DPRGMYQCKG SQNKSKPLQV YYRMCQNCIE LNAATIS. | |
| Precautions | |
| CD3e Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P07766 ) | |
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ADMEbio Team
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