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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| CDA0072-50 | 7 days | 50 µg | $400.00 |
Select product before adding to cart
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| CDA0072-100 | 7 days | 100 µg | $600.00 | |||
| CDA0072-1 | 7 days | 1 mg | $2,400.00 |
Product Overview | |
| Name | CD4 Human (125-202) |
|---|---|
| Description | |
| CD-4 (125-202 a.a.) Human Recombinant | |
| Synonyms | |
| gp55, HLA-2, L3 / T4, Ly-4, T cell antigen T4/LEU3, T4, sCD4. | |
| Introduction | |
| CD4, a single chain transmembrane glycoprotein, is found on a T cell subset (helper/inducer) representing 45% of peripheral blood lymphocytes. It is also present on 80% of thymocytes and at a lower level on monocytes. It is involved in recognition of antigen presented along with MHC class II by APCs. It serves as receptor for HIV. Antibody to CD4 recognizes T-helper cells required for recognition of class II antigens. It reacts with ~60% of peripheral blood E rosette-positive (E+) cells while showing negligible reactivity with E- cells, monocytes, granulocytes, EBV-transformed B cell lines, and mouse splenocytes. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile lyophilized powder. | |
| Formulation | |
| Each mg contains 1X PBS, 0.1% SDS and 1mM DTT. | |
| Stability | |
| Store vial at -20oC to -80oC. When stored at the recommended temperature, this protein is stable for 12 months. Please avoid freeze-thaw cycles. | |
| Solubility | |
| It is recommended to reconstitute the lyophilized CD-4 (203-317) in sterile 18MΩ-cm H 2 O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. | |
| Precautions | |
| CD4 Human (125-202) is for research use only and not for use in diagnostic or therapeutic procedures. | |
References |
Title :Reduced Monomeric CD4 Is the Preferred Receptor for HIV. Publication : 10.1074/jbc.M110.190579 December 24, 2010 The Journal of Biological Chemistry, 285, 40793-40799. Link: http://www.jbc.org/content/285/52/40793.full#fn-1 |
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ADMEbio Team
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