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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| CDA0148-5 | 7 days | 5 µg | $120.00 |
Select product before adding to cart
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| CDA0148-20 | 7 days | 20 µg | $290.00 | |||
| CDA0148-1 | 7 days | 1 mg | $4,320.00 |
Product Overview | |
| Name | sCD40L Human, His |
|---|---|
| Description | |
| soluble CD40 Ligand/TRAP Human Recombinant, His Tag | |
| Accession (Primary) | P29965 |
| Synonyms | |
| CD40 ligand, CD154, CD40L, gp39, hCD40L, HIGM1, IGM, IMD3, T-BAM, TNFSF5, TRAP. | |
| Introduction | |
| CD40L or CD154 is a membrane glycoprotein and differentiation antigen expressed on the surface of T-cells. The CD40 ligand stimulates B-cell proliferation and secretion of all immunoglobulin isotypes in the presence of cytokines. CD40 ligand has been shown to induce cytokine production and tumoricidal activity in peripheral blood monocytes. It also costimulates proliferation of activated T-cells and this is accompanied by the production of IFN-gamma , TNF-alpha , and IL2. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered colorless solution. | |
| Formulation | |
| sCD40L protein (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.2M NaCl, 1mM DTT and 40% glycerol. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 95.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| MGSSHHHHHH SSGLVPRGSH MQKGDQNPQI AAHVISEASS KTTSVLQWAE KGYYTMSNNL VTLENGKQLT VKRQGLYYIY AQVTFCSNRE ASSQAPFIAS LCLKSPGRFE RILLRAANTH SSAKPCGQQS IHLGGVFELQ PGASVFVNVT DPSQVSHGTG FTSFGLLKL | |
| Biological Activity | |
| Measured by its binding ability in a functional ELISA with Human CD40/TNFRSF5. | |
| Precautions | |
| sCD40L Human, His is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P29965 ) | |
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ADMEbio Team
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ADMEbio Team
