Hello, Sign in
My Account
My Account
New customer? Start here
| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP0388-5 | 7 days | 5 µg | $120.00 |
Select product before adding to cart
|
||
| RCP0388-20 | 7 days | 20 µg | $290.00 | |||
| RCP0388-1 | 7 days | 1 mg | $8,320.00 |
Product Overview | |
| Name | CENPA Human |
|---|---|
| Description | |
| Centromere Protein A Human Recombinant | |
| Accession (Primary) | P49450 |
| Synonyms | |
| Major centromere autoantigen B, Centromere protein B, CENP-B, CENPB. | |
| Introduction | |
| Centromere proteins are a group of proteins which form and/or mediate the function of centromeres, the central structures of chromosomes to which spindle fibers/microtubuli attach and pull the chromosomes apart in cell division. Currently, 9 centromere proteins are known and designated CENPA to CENP-I. Most of the centromere proteins are targets of autoantibodies, the anti-centromere antibodies. CENPB is the most important of the centromeric autoantigens: it has a molecular weight of approx. 66 kDa and plays an important role in the formation of the centromeric chromatin. CENPB antibodies are present in the sera of up to 80% of patients with CREST syndrome. | |
| Source | |
| Sf9 insect cells. | |
| Physical Appearance | |
| Sterile Filtered liquid formulation. | |
| Formulation | |
| CENPB is supplied at a concentration of in 20mM HEPES buffer pH-7.6, 250mM NaCl and 20% glycerol. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 95% as determined by SDS-PAGE. | |
| Coating concentration | |
| 0.15-0.375 µg/ml (depending on the type of ELISA plate and coating buffer). Suitable for biotinylation and iodination. | |
| Precautions | |
| CENPA Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P49450 ) | |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from ADMEbio to advance their research.
Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
Thank you,
ADMEbio Team
ADMEbio welcomes feedback from our customers.
Thank you,
ADMEbio Team
