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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| CHK0082-5 | 7 days | 5 µg | $120.00 |
Select product before adding to cart
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| CHK0082-25 | 7 days | 25 µg | $290.00 | |||
| CHK0082-1 | 7 days | 1 mg | $4,320.00 |
Product Overview | |
| Name | IP 10 Human |
|---|---|
| Description | |
| IP-10 Human Recombinant (CXCL10) | |
| Accession (Primary) | P02778 |
| Synonyms | |
| Small inducible cytokine B10, CXCL10, 10 kDa interferon-gamma-induced protein, Gamma-IP10, IP-10, chemokine (C-X-C motif) ligand 10, C7, IFI10, INP10, crg-2, mob-1, SCYB10, gIP-10. | |
| Introduction | |
| Chemokine (C-X-C motif) ligand 10 (CXCL10) is a small cytokine belonging to the CXC chemokine family that is also known as 10 kDa interferon-gamma-induced protein (?-IP10 or IP-10). CXCL10 is secreted by several cell types in response to IFN-?. These cell types include monocytes, endothelial cellsand fibroblasts. CXCL10 has been attributed to several roles, such as chemoattraction for monocytesand T cells, promotion of T cell adhesion to endothelial cells, anti tumor activity, and inhibition of bone marrow colony formation and angiogenesis. The gene for CXCL10 is located on human chromosome 4in a cluster among several other CXC chemokines. This chemokine elicits its effects by binding to the cell surface chemokine receptor CXCR3. The three-dimensional crystal structure of this chemokine has been determined under 3 different conditions to a resolution of up to 1.92A. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered clear solution. | |
| Formulation | |
| IP-10 His is supplied in 10mM Tris HCl pH8, 1mM EDTA and 50% glycerol. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles. | |
| Purity | |
| Greater than 95.0% as determined by(a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. | |
| Precautions | |
| IP 10 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P02778 ) | |
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ADMEbio Team
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ADMEbio Team
