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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| CHK0139-5 | 7 days | 5 µg | $120.00 |
Select product before adding to cart
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| CHK0139-25 | 7 days | 25 µg | $290.00 | |||
| CHK0139-1 | 7 days | 1 mg | $4,320.00 |
Product Overview | |
| Name | MIP 5 Human |
|---|---|
| Description | |
| Macrophage Inflammatory Protein-5 Human Recombinant (CCL15) | |
| Accession (Primary) | Q16663 |
| Synonyms | |
| CCL9/10, MRP2, CCF18. | |
| Introduction | |
| Mouse MIP-1 gamma is 75% identical in its amino acid compostion as compared to the rat specie. MIP-1 gamma is a CC chemokine localized in murine blood and a widespread range of murine tissues, without having an identified human homolog. MIP-1 gamma signals through the CCR1 receptor. MIP-1 gamma chemoattracts neutrophils and also inhibits colony formation of bone marrow myeloid immature progenitors. MIP-1 gamma has six cysteines including the four highly conserved cysteine residues present in CC chemokines. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| The MIP-1 gamma was lyophilized from 1xPBS solution pH-7.4. | |
| Stability | |
| Lyophilized MIP-1 gamma although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CCL9/10 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 97.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. | |
| Amino acid sequence | |
| QITHATETKE VQSSLKAQQG LEIEMFHMGF QDSSDCCLSY NSRIQCSRFI GYFPTSGGCT RPGIIFISKR GFQVCANPSD RRVQRCIERL EQNSQPRTYK Q. | |
| Biological Activity | |
| Defined by its ability to chemoattract human neutrophils using a concentration range of 0.1-10 ng/ml, corresponding to a Specific Activity of 10,000-100,000IU/mg. | |
| Solubility | |
| It is recommended to reconstitute the lyophilized MIP-1 gamma in sterile 18M-cm H2O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. | |
| Precautions | |
| MIP 5 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q16663 ) | |
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ADMEbio Team
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