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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| CHK0143-2 | 7 days | 2 µg | $120.00 |
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| CHK0143-10 | 7 days | 10 µg | $290.00 | |||
| CHK0143-1 | 7 days | 1 mg | $4,320.00 |
Product Overview | |
| Name | NAP 2 Human |
|---|---|
| Description | |
| Neutrophil Activating Protein-2 Human Recombinant (CXCL7) | |
| Accession (Primary) | P02775 |
| Synonyms | |
| Platelet basic protein, PBP, Small inducible cytokine B7, CXCL7, Leukocyte-derived growth factor, LDGF, Macrophage-derived growth factor, MDGF, pro-platelet basic protein (chemokine (C-X-C motif) ligand 7), TC1, TC2, TGB, TGB1, B-TG1, CTAP3, NAP-2, SCYB7, THBGB, LA-PF4, THBGB1, Beta-TG, CTAPIII, CTAP-III. | |
| Introduction | |
| Chemokine (C-X-C motif) ligand (CXCL7) is a small cytokine belonging to the CXC chemokine family. It is a protein that is released in large amounts from platelets following their activation. It stimulates various processes including mitogenesis, synthesis of extracellular matrix, glucose metabolism and synthesis of plasminogen activator. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| NAP-2 protein was lyophilized from a 0.2 µm filtered concentrated solution in 1×PBS, pH 7.4. | |
| Stability | |
| Lyophilized NAP-2 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CXCL7 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 97.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. | |
| Amino acid sequence | |
| IELRCRCTNT LSGIPLNSIS RVNVFRPGAH CDNVEVIATL KNGKEVCLDP TAPMIKKIVK KI. | |
| Biological Activity | |
| Measured by its ability to chemoattract BaF3 mouse pro-B cells transfected with human CXCR2. The ED 50 for this effect is less than 10ng/ml, corresponding to a specific activity of 100,000units/mg. | |
| Solubility | |
| It is recommended to reconstitute the lyophilized NAP-2 in sterile 18M-cm H 2 O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. | |
| Precautions | |
| NAP 2 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P02775 ) | |
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ADMEbio Team
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