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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| CHK0145-5 | 7 days | 5 µg | $120.00 |
Select product before adding to cart
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| CHK0145-20 | 7 days | 20 µg | $290.00 | |||
| CHK0145-1 | 7 days | 1 mg | $4,320.00 |
Product Overview | |
| Name | PF 4 Human |
|---|---|
| Description | |
| Platelet Factor-4 Human Recombinant (CXCL4) | |
| Accession (Primary) | P02776 |
| Synonyms | |
| CXCL4, PF-4, PF4, Iroplact, Oncostatin-A, SCYB4, MGC138298. | |
| Introduction | |
| Platelet factor-4 is a 70-amino acid protein that is released from the alpha-granules of activated platelets. Its major physiologic role appears to be neutralization of molecules on the endothelial surface of blood vessels, thereby inhibiting local activity and promoting coagulation. As a strong chemoattractant for neutrophils and fibroblasts, PF4 probably has a role in inflammation and wound repair. Oncostatin-A is a member of the CXC chemocinfamily. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered white lyophilized powder. | |
| Formulation | |
| The Mouse CXCL4 protein was lyophilized from a 0.2 µm filtered concentrated solution in 20mM PB, pH 7.4 and 1.5M NaCl. | |
| Stability | |
| Lyophilized CXCL4 Mouse Recombinant although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Mouse CXCL4 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 97.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. | |
| Amino acid sequence | |
| VTSAGPEESD GDLSCVCVKT ISSGIHLKHI TSLEVIKAGR HCAVPQLIAT LKNGRKICLD RQAPLYKKVI KKILES. | |
| Biological Activity | |
| Determined by its ability to chemoattract human neutrophils using a concentration range of 10-100ng/ml. | |
| Solubility | |
| It is recommended to reconstitute the lyophilized CXCL4 in sterile 18MΩ-cm H 2 O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. | |
| Precautions | |
| PF 4 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P02776 ) | |
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ADMEbio Team
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