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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| CHK0173-5 | 7 days | 5 µg | $120.00 |
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| CHK0173-20 | 7 days | 20 µg | $290.00 | |||
| CHK0173-1 | 7 days | 1 mg | $4,320.00 |
Product Overview | |
| Name | TARC Rat |
|---|---|
| Description | |
| Thymus and Activation Regulated Chemokine (CCL17) Rat Recombinant | |
| Accession (Primary) | Q9ERE0 |
| Synonyms | |
| ALS10, TDP43, TAR DNA-binding protein 43, TDP-43, TARDBP. | |
| Introduction | |
| TAR DNA Binding Protein (TARDBP) was initially recognized as a transcriptional repressor which binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, TARDBP has been detected in individuals diagnosed with chronic traumatic encephalopathy as well, which is a condition that often imitates ALS and has been related with athletes who have experienced multiple concussions and other types of head injury . TARDBP has been shown to bind both DNA and RNA, it has multiple functions in transcriptional repression, pre-mRNA splicing and translational regulation . | |
| Source | |
| E.coli. | |
| Physical Appearance | |
| Sterile Filtered colorless solution. | |
| Formulation | |
| TARDBP protein solution (0.25mg/ml) containing 20mM Tris-HCl (pH8.0), 1mM DTT, 0.1M NaCl, 10% glycerol and 1mM EDTA. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 85% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| MSEYIRVTED ENDEPIEIPS EDDGTVLLST VTAQFPGACG LRYRNPVSQC MRGVRLVEGI LHAPDAGWGN LVYVVNYPKD NKRKMDETDA SSAVKVKRAV QKTSDLIVLG LPWKTTEQDL KEYFSTFGEV LMVQVKKDLK TGHSKGFGFV RFTEYETQVK VMSQRHMIDG RWCDCKLPNS KQSQDEPLRS RKVFVGRCTE DMTEDELREF FSQYGDVMDV FIPKPFRAFA FVTFADDQIA QSLCGEDLII KGISVHISNA EPKHNSNRQL ERSGRFGGNP GGFGNQGGFG NSRGGGAGLG NNQGSNMGGG MNFGAFSINP AMMAAAQAAL QSSWGMMGML ASQQNQSGPS GNNQNQGNMQ REPNQAFGSG NNSYSGSNSG AAIGWGSASN AGSGSGFNGG FGSSMDSKSS GWGM. | |
| Precautions | |
| TARC Rat is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q9ERE0 ) | |
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ADMEbio Team
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ADMEbio Team
