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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| CYK0042-20 | 7 days | 20 µg | $400.00 |
Select product before adding to cart
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| CYK0042-100 | 7 days | 100 µg | $1,000.00 | |||
| CYK0042-1 | 7 days | 1 mg | $3,840.00 |
Product Overview | |
| Name | APOA1 |
|---|---|
| Description | |
| Apolipoprotein A-I Human | |
| Accession (Primary) | P02647 |
| Immunogen | |
| Anti-human APOA1, is derived from hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice immunized with recombinant human APOA1 amino acids 25-267 purified from E. coli. | |
| Synonyms | |
| Apolipoprotein A-I, Apo-AI, ApoA-I, APOA1, MGC117399. | |
| Introduction | |
| APOA1 (Apolipoprotein A-1) is a human protein with a specific role in lipid metabolism being the main protein component of HDL in the plasma. APOA1 promotes cholesterol efflux from tissues to the liver for excretion. Furthermore, APOA1 is a cofactor for LCAT, which is responsible for the formation of most plasma cholesteryl esters. In addition, APOA1 activates spermatozoa motility as part of the SPAP complex. The APOA1 gene is strongly linked with two other apolipoprotein genes on chromosome 11. Defects in the APOA1 gene are linked to HDL deficiency including Tangier disease, and with systemic non-neuropathic amyloidosis. High levels of APOA1 are linked to the manifestation of asthma and atopy. | |
| Formulation | |
| 1mg/ml containing PBS, pH-7.4, 10% Glycerol and 0.02% Sodium Azide. | |
| Applications | |
| The antibody has been tested by ELISA, Western blot analysis, Flow cytometry and ICC/IF to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. | |
| Type | |
| Mouse Anti Human Monoclonal. | |
| Clone | |
| PAT1E12AT. | |
| Ig Subclass | |
| Mouse IgG 2a heavy chain and k light chain. | |
| Purification Method | |
| APOA1 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography. | |
| Storage Procedures | |
| For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. | |
| Precautions | |
| APOA1 is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P02647 ) | |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from ADMEbio to advance their research.
Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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ADMEbio Team
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ADMEbio Team
