| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| CYK0061-5 | 7 days | 5 µg | $120.00 |
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| CYK0061-20 | 7 days | 20 µg | $290.00 | |||
| CYK0061-1 | 7 days | 1 mg | $4,320.00 |
Product Overview | |
| Name | APRIL Mouse |
|---|---|
| Description | |
| APRIL Mouse Recombinant | |
| Accession (Primary) | Q9D777 |
| Synonyms | |
| Pancreatic trypsin inhibitor, Basic protease inhibitor, BPI, BPTI, Aprotinin, AP. | |
| Introduction | |
| Aprotinin inhibits the activity of several proteolytic enzymes such as chymotrypsin, kallikrein, plasmin and trypsin. Aprotinin is present in blood and in most tissues, with a high concentration in lung. Aprotinin inhibits pro-inflammatory cytokine release and maintains glycoprotein homeostasis. In platelets, aprotinin reduces glycoprotein loss (e.g., GpIb, GpIIb/IIIa), while in granulocytes it prevents the expression of pro-inflammatory adhesive glycoproteins (e.g., CD11b). | |
| Source | |
| Bovine Lung. | |
| Physical Appearance | |
| Sterile Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| The protein (1mg/ml) was lyophilized with no additives. | |
| Stability | |
| Lyophilized Aprotinin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Aprotinin should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. | |
| Solubility | |
| It is recommended to reconstitute the lyophilized Aprotinin in sterile 18MΩ-cm H2O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. | |
| Specific Activity | |
| 6,120 KIU (Kallikrein Inactivator Units) per mg, 3.4 pH.Eur.U/mg. | |
| Precautions | |
| APRIL Mouse is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q9D777 ) | |
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Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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ADMEbio Team
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ADMEbio Team