| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| CYK0062-5 | 7 days | 5 µg | $120.00 |
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| CYK0062-20 | 7 days | 20 µg | $290.00 | |||
| CYK0062-1 | 7 days | 1 mg | $7,488.00 |
Product Overview | |
| Name | BAFF Human |
|---|---|
| Description | |
| B-cell Activating Factor Human Recombinant | |
| Accession (Primary) | Q9Y275 |
| Synonyms | |
| BAFF, BLYS, CD257, TALL1, THANK, ZTNF4, TALL-1, TNFSF20, TNFSF13B, B-cell Activating Factor. | |
| Introduction | |
| Binds to tnfrsf13b/taci and tnfrsf17/bcma. tnfsf13/april binds to the same 2 receptors, together, they form a 2 ligands -2 receptors pathway involved in the stimulation of b- and t-cell function and the regulation of humoral immunity. a third b-cell specific baff-receptor (baffr/br3) promotes the survival of mature b-cells and the b-cell response. B Lymphocyte Stimulator functions as a potent B-cell growth factor in costimulation assays. Administration of BAFF Human recombinant to mice disrupts splenic B-cell and T-cell zones and results in elevated levels of serum immunoglobulin. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered colorless solution. | |
| Formulation | |
| Recombinant His Tag BAFF contains PBS pH-7.4 and 10% glycerol. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 95.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHM AV QGPEETVTQD CLQLIADSET PTIQKGSYTF VPWLLSFKRG SALEEKENKI LVKETGYFFI YGQVLYTDKT YAMGHLIQRK KVHVFGDELS LVTLFRCIQN MPETLPNNSC YSAGIAKLEE GDELQLAIPR ENAQISLDGD VTFFGALKLL | |
| Precautions | |
| BAFF Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q9Y275 ) | |
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ADMEbio Team
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ADMEbio Team