| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| CYK0073-5 | 7 days | 5 µg | $120.00 |
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| CYK0073-20 | 7 days | 20 µg | $290.00 | |||
| CYK0073-1 | 7 days | 1 mg | $4,320.00 |
Product Overview | |
| Name | BD 3 Mouse |
|---|---|
| Description | |
| Beta Defensin-3 Mouse Recombinant | |
| Accession (Primary) | Q9WTL0 |
| Synonyms | |
| Beta-defensin 3, BD-3, Defensin beta 3, Defb3. | |
| Introduction | |
| Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 103A, which has broad spectrum antimicrobial activity and may play an important role in innate epithelial defense. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| BD-3 protein was lyophilized from a 0.2 µm filtered concentrated solution in PBS, pH 7.4. | |
| Stability | |
| Lyophilized BD-3 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution BD-3 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 98.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. | |
| Amino acid sequence | |
| KKVYNAVSCM TNGGICWLKC SGTFREIGSC GTRQLKCCKK K. | |
| Biological Activity | |
| Measured by its antimicrobial activity against E. coli. The ED 50 for this effect is typically 4-20 µg/ml, corresponding to a specific activity of 50,000-250,000units/mg. | |
| Solubility | |
| It is recommended to reconstitute the lyophilized BD-3 in sterile 18M-cm H 2 O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. | |
| Precautions | |
| BD 3 Mouse is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q9WTL0 ) | |
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