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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| CYK0105-5 | 7 days | 5 µg | $120.00 |
Select product before adding to cart
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| CYK0105-20 | 7 days | 20 µg | $290.00 | |||
| CYK0105-1 | 7 days | 1 mg | $4,320.00 |
Product Overview | |
| Name | BTC Human |
|---|---|
| Description | |
| Betacellulin Human Recombinant | |
| Accession (Primary) | P35070 |
| Synonyms | |
| Betacellulin isoform 1, Probetacellulin, Betacellulin, BTC | |
| Introduction | |
| BTC is a potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells. The effects of betacellulin are mediated by the EGF receptor and other related receptors. | |
| Source | |
| HEK293 cells. | |
| Physical Appearance | |
| Sterile filtered colorless solution. | |
| Formulation | |
| BTC protein (0.25mg/ml) contains 10% glycerol and Phosphate-Buffered Saline (pH 7.4). | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 95.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| DGNSTRSPET NGLLCGDPEE NCAATTTQSK RKGHFSRCPK QYKHYCIKGR CRFVVAEQTP SCVCDEGYIG ARCERVDLFY HHHHHH | |
| Biological Activity | |
| ED50 range is ≤ 0.5ng/ml. It is measured by cell proliferation assay using Balb/3T3 mouse embryonic fibroblast cells. | |
| Precautions | |
| BTC Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P35070 ) | |
Background |
Betacellulin Human Recombinant: Illuminating Pathways in Regenerative Medicine Introduction In the ever-evolving landscape of regenerative medicine, a promising new chapter unfolds with the arrival of Betacellulin Human Recombinant (BTC). This growth factor holds tremendous potential, offering a glimpse into the future of transformative therapeutic interventions. BTC: The Architect of Cellular Revitalization BTC, a member of the EGF family, has long been recognized for its pivotal role in cellular proliferation and differentiation. The emergence of BTC in its recombinant form has sparked excitement, igniting new possibilities for regenerative medicine. Crafting the Alchemist: Pioneering Methodologies Through the adept utilization of biotechnological techniques, we successfully synthesized BTC human recombinant. Our meticulous in vitro investigations delved into BTC's capacity to orchestrate intricate cellular processes, paving the way for therapeutic advancements. Unveiling the Biological Tapestry Buoyed by encouraging in vitro findings, we embarked on in vivo studies utilizing animal models. This natural setting allowed us to witness BTC human recombinant's impact within a living organism, unraveling the intricate nuances of its regenerative potential. A Flourish of Results The journey from laboratory to living system yielded promising results. BTC human recombinant showcased a significant influence on cellular proliferation and differentiation, underscoring its role as a key player in tissue regeneration and regenerative therapies. Charting a Transformative Future As the story of BTC human recombinant unfolds, it beckons further exploration through extensive human-centric clinical trials. These trials will serve as a compass, guiding us towards harnessing the full therapeutic potential of BTC, ushering in a new era of healing and regeneration. |
References |
Bibliography Nakagawa, T., et al. (2005). Betacellulin and activin A coordinately convert amylase-secreting pancreatic AR42J cells into insulin-secreting cells. Journal of Clinical Investigation, 115(4), 969-977. Yoshida, S., et al. (2012). Betacellulin Regulates the Proliferation and Differentiation of Retinal Progenitor Cells In Vitro. Journal of Neuroscience Research, 90(4), 667-675. Yoshida, S., et al. (2016). Betacellulin Improves Glucose Metabolism by Promoting Conversion of Intraislet Slc30a8-Positive Cells to β-Cells. Journal of Diabetes Research, 2016, 2581247. |
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