| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| CYK0127-2 | 7 days | 2 µg | $120.00 |
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| CYK0127-10 | 7 days | 10 µg | $290.00 | |||
| CYK0127-1 | 7 days | 1 mg | $8,320.00 |
Product Overview | |
| Name | CYTL1 Human |
|---|---|
| Description | |
| Cytokine-Like 1 Human Recombinant | |
| Accession (Primary) | Q9NRR1 |
| Synonyms | |
| CYCS, CYC, cyt c | |
| Source | |
| Bovine. | |
| Physical Appearance | |
| Reddish or dark brown crystalline powder. | |
| Formulation | |
| The protein (1mg/ml) was lyophilized with no additives. | |
| Stability | |
| Lyophilized Cytochrome-C Bovine although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Cytochrome-C Bovine should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 99.0%. | |
| Solubility | |
| It is recommended to reconstitute the lyophilized Cytochrome-C Bovine in sterile 18MΩ-cm H 2 O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. | |
| Background | |
| Bovine Cytochrome c in Health and Disease: Understanding the behavior of Cytochrome c in bovine systems has implications for veterinary medicine and livestock health. Alterations in mitochondrial function, reflected in changes in Cytochrome c dynamics, may be indicative of metabolic disorders, oxidative stress, or other pathological conditions. Bovine Cytochrome c studies contribute to our knowledge of mitochondrial dysfunction in diseases affecting cattle, potentially paving the way for diagnostic and therapeutic strategies. Challenges and Future Directions: While the study of Cytochrome c in bovine systems provides a wealth of insights, challenges persist. Fine-tuning experimental methodologies, exploring the interplay with other mitochondrial components, and deciphering the specificities in bovine systems are critical considerations for advancing our understanding. Additionally, linking changes in Cytochrome c behavior to specific physiological outcomes in cattle poses a challenge, requiring comprehensive investigations in diverse contexts. Bovine Cytochrome c emerges as a sentinel player in the intricate dance of cellular respiration, offering a window into the energetic dynamics of bovine mitochondria. Its structural insights, functional significance, and implications in health and disease position it as a central focus in understanding cellular bioenergetics in cattle. As researchers continue to unravel the molecular intricacies of bovine Cytochrome c, they not only deepen our understanding of mitochondrial function but also contribute to advancements in veterinary medicine and the optimization of livestock health, shaping the future of sustainable and healthy cattle farming practices. | |
| Precautions | |
| CYTL1 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q9NRR1 ) | |
Background |
Title: Cytokine-Like 1 Human Recombinant: Exploring its Role in Immune Regulation and Therapeutic Potential Abstract: Cytokine-like 1 (CYTL1) is an emerging cytokine that exhibits pleiotropic effects on immune regulation and tissue homeostasis. This research paper provides a comprehensive analysis of human recombinant CYTL1, focusing on its production, characterization, and potential applications in immune modulation. The paper highlights the significance of CYTL1 in immune cell function, inflammation, and tissue repair. Furthermore, it explores ongoing research and clinical trials investigating the therapeutic potential of recombinant CYTL1 in various pathological conditions. The information presented in this paper aims to enhance our understanding of human recombinant CYTL1 and its utility as a research tool and a potential immunotherapeutic agent. Introduction: Cytokine-like 1 (CYTL1) is a recently discovered cytokine with diverse biological functions, including immune regulation and tissue repair. Human recombinant CYTL1, produced through genetic engineering techniques, provides researchers with a valuable tool to study its biological activities and explore its therapeutic potential. Production and Characterization: Recombinant CYTL1 is typically generated using expression systems such as mammalian cells or bacteria. The protein is then purified and characterized to ensure its structural integrity and functional activity. Rigorous quality control measures are implemented to confirm the specificity and bioactivity of the recombinant CYTL1. Role in Immune Regulation: CYTL1 has been shown to modulate immune cell function and inflammation. It can influence the differentiation and activation of various immune cell subsets, including T cells and macrophages. Recombinant CYTL1 serves as a valuable tool for investigating the mechanisms underlying immune regulation and exploring its potential as an immunomodulatory agent. Therapeutic Implications: The dysregulation of immune responses is associated with numerous pathological conditions, including autoimmune diseases and chronic inflammation. Recombinant CYTL1 holds promise as a potential immunotherapeutic agent due to its ability to modulate immune cell function and regulate inflammatory processes. Ongoing research and clinical trials are investigating the therapeutic applications of recombinant CYTL1 in various diseases, including autoimmune disorders and tissue regeneration. Conclusion: Human recombinant CYTL1 is a valuable research tool and a potential immunotherapeutic agent. Its production, characterization, and applications in immune regulation contribute to our understanding of immune responses and the development of targeted therapeutic interventions. Continued research and clinical trials exploring the therapeutic potential of recombinant CYTL1 offer promising avenues for improving outcomes in autoimmune diseases, chronic inflammation, and tissue repair. |
References |
Bibliography: Jin, H., Sun, J., Yang, F., et al. (2019). Cytokine-like 1 suppresses hepatic glucose production through the regulation of gluconeogenesis and glycogen synthesis. Cell Death & Disease, 10(1), 1-15. Liu, Z., Li, X., Gou, W., et al. (2020). Cytokine-like 1 regulates adipose tissue homeostasis to promote metabolic health. Journal of Molecular Cell Biology, 12(8), 622-633. Ma, H., Zhang, X., Wu, H., et al. (2019). CYTL1 inhibits chondrogenic differentiation of mesenchymal stem cells through Wnt/β-catenin signaling pathway. Cell Death & Disease, 10(1), 1-14. Park, J. E., Kim, D. Y., Cheol Lee, J., et al. (2016). Cytokine-like 1 knock-out mice (Cytl1−/−) show normal adipogenesis and wound healing. Scientific Reports, 6(1), 1-11. Shen, Y., Qiao, X., Li, G., et al. (2020). Cytokine-like 1 enhances Th17 differentiation and aggravates experimental autoimmune encephalomyelitis. Frontiers in Immunology, 11, 1-13 |
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