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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| CYK0135-2 | 7 days | 2 µg | $120.00 |
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| CYK0135-10 | 7 days | 10 µg | $290.00 | |||
| CYK0135-1 | 7 days | 1 mg | $7,680.00 |
Product Overview | |
| Name | EBI3 Human, His |
|---|---|
| Description | |
| Epstein Barr Virus Induced 3 Human Recombinant, His Tag | |
| Accession (Primary) | Q14213 |
| Synonyms | |
| IL-27B, IL27B, IL 27-B, EBI-3, Interleukin-27 beta, IL-27 subunit beta, Epstein-Barr virus-induced gene 3 protein homolog, EBI3. | |
| Introduction | |
| EBI3 has an induced expression in B lymphocytes in reaction to Epstein-Barr virus infection. EBI3 encodes a secreted glycoprotein belonging to the hematopoietin receptor family, and heterodimerizes with a 28 kDa protein to form iIL-27. EBI3 drives rapid clonal expansion of naive cd4(+) t-cells. EBI3 strongly synergizes with IL-12 to activate IFN-gamma production of naive cd4(+) t-cells. EBI3 mediates its biologic effects through the cytokine receptor wsx-1/tccr. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| Lyophilized from a sterile filtered solution containing 0.1 % trifluoroacetic acid (TFA). | |
| Stability | |
| Lyophilized EBI3 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution EBI3 Macaque should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 95.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| MRKGPPAALT LPRVQCRAPR YPIAVDCSWT LPPAPNSTSP VSFIATYRFG MAARGHSWPC LQQTPASTSC TIADVRLFSM APYVLNVTAV HPWGSSSSFV PFIAEHIIKP DPPEGVRLSP LAERQLQVQW EPPRSWPFPE IFSLKYWIRY KRQGAARFHQ VGPIEATSFI LRAVRPRARY CVQVAAQDLT DYGELSDWSL PATTPMSPGK. | |
| Solubility | |
| It is recommended to reconstitute the lyophilized EBI3 in sterile 18MΩ-cm H 2 O at a concentration of 100 µg/ml, which can then be further diluted to other aqueous solutions. | |
| Precautions | |
| EBI3 Human, His is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q14213 ) | |
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ADMEbio Team
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ADMEbio Team
