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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| CYK0145-2 | 7 days | 2 µg | $120.00 |
Select product before adding to cart
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| CYK0145-10 | 7 days | 10 µg | $290.00 | |||
| CYK0145-100 | 7 days | 100 µg | $1,920.00 |
Product Overview | |
| Name | EREG Human, HEK |
|---|---|
| Description | |
| Epiregulin Human Recombinant, HEK | |
| Accession (Primary) | O14944 |
| Synonyms | |
| Epiregulin, Proepiregulin, ER, ERP. | |
| Introduction | |
| Epiregulin is part of the EGF family. Epiregulin functions as a ligand of EGFR, as well as a ligand of most members of the ERBB (v-erb-b2 oncogene homolog) family of tyrosine-kinase receptors.Epiregulin is expressed mostly in the placenta and peripheral blood leukocytes and in specific carcinomas of the bladder, lung, kidney and colon. Epiregulin stimulates the proliferation of keratinocytes, hepatocytes, fibroblasts and vascular smooth muscle cells. Epiregulin inhibits the growth of several tumor-derived epithelial cell lines. Human Epiregulin is initially synthesized as a glycosylated 19.0 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce a 6.0 kDa mature secreted sequence. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered colorless solution. | |
| Formulation | |
| EREG protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH8.0) and 10% glycerol. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 80.0% as determined by SDS-PAGE | |
| Amino acid sequence | |
| MGSSHHHHHH SSGLVPRGSH MGS VSITKCS SDMNGYCLHG QCIYLVDMSQ NYCRCEVGYT GVRCEHFFL. | |
| Precautions | |
| EREG Human, HEK is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( O14944 ) | |
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Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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ADMEbio Team
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ADMEbio Team
