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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| CYK0147-5 | 7 days | 5 µg | $120.00 |
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| CYK0147-20 | 7 days | 20 µg | $290.00 | |||
| CYK0147-1 | 7 days | 1 mg | $5,616.00 |
Product Overview | |
| Name | FAS Human |
|---|---|
| Description | |
| sFas Receptor Human Recombinant | |
| Accession (Primary) | P25445 |
| Synonyms | |
| CD95, CD-95, Tumor necrosis factor receptor superfamily member 6, FASLG receptor, Apoptosis-mediating surface antigen FAS, Apo-1 antigen, CD95 antigen, FAS, APT1, FAS1, TNFRSF6, APO-1, FASTM, ALPS1A. | |
| Introduction | |
| FAS / CD95 is a 36kDa transmembrane type I receptor, which belongs to the NF/NGF receptor super-family. It is a potent inducer of apoptosis in cells of the immune system upon interaction with its natural ligand, CD95L. Although the CD95/CD95L system could play a role in tumor regression, tumor cells seem to down-regulate CD95 expression as a mechanism of resistance to CD95L-induced killing by T lymphocytes and NK cells. The Fas antigen is expressed on the surface of various cell types, including activated T and B lymphocytes and T lymphoblastoid cell line. CD95 is also expressed in a broad panel of non-transformed cells outside the immune system. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile liquid formulation. | |
| Formulation | |
| 10mM Sodium Phosphate, pH 8.0. | |
| Stability | |
| CD95 although stable at 10°C for 5 days, should be stored below -18°C. Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 95% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. | |
| Precautions | |
| FAS Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P25445 ) | |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from ADMEbio to advance their research.
Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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ADMEbio Team
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ADMEbio Team
