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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| CYK0168-5 | 7 days | 5 µg | $120.00 |
Select product before adding to cart
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| CYK0168-20 | 7 days | 20 µg | $290.00 | |||
| CYK0168-1 | 7 days | 1 mg | $5,760.00 |
Product Overview | |
| Name | GDF10 Human |
|---|---|
| Description | |
| Growth differentiation factor 10 Human Recombinant | |
| Accession (Primary) | P55107 |
| Synonyms | |
| Growth Differentiation Factor 11, GDF-11, Bone Morphogenetic Protein 11, BMP11. | |
| Introduction | |
| GDF-11 belongs to the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. GDF-11 is a central developmental factor which controls muscular and neural development. In adults, GDF-11 encourages cardiac hypertrophy reverse by the revival of cardiomyocytes. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| Lyophilized from a concentrated (1mg/ml) solution containing 0.1% Trifluoroacetic Acid (TFA). | |
| Stability | |
| Lyophilized GDF11 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution GDF11 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 95.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| NLGLDCDEHS SESRCCRYPL TVDFEAFGWD WIIAPKRYKA NYCSGQCEYM FMQKYPHTHL VQQANPRGSA GPCCTPTKMS PINMLYFNDK QQIIYGKIPG MVVDRCGCS | |
| Biological Activity | |
| The ED 50 as determined by the ability to inhibit alkaline phosphatase activity in ATDC5 cells, is 0.2-0.3ng/ml, corresponding to a specific activity of 5 x 10 6 units/mg. | |
| Solubility | |
| It is recommended to reconstitute the lyophilized GDF11 in sterile 18M-cm H2O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. | |
| Precautions | |
| GDF10 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P55107 ) | |
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ADMEbio Team
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ADMEbio Team
