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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| CYK0183-2 | 7 days | 2 µg | $120.00 |
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| CYK0183-10 | 7 days | 10 µg | $290.00 | |||
| CYK0183-1 | 7 days | 1 mg | $8,320.00 |
Product Overview | |
| Name | IFI30 Human |
|---|---|
| Description | |
| IFN Gamma-Inducible protein 30 Human Recombinant | |
| Accession (Primary) | P13284 |
| Synonyms | |
| Interferon-induced helicase C domain-containing protein 1, Clinically amyopathic dermatomyositis autoantigen 140 kDa, CADM-140 autoantigen, Helicase with 2 CARD domains, Helicard, Interferon-induced with helicase C domain protein 1, Melanoma differentiation-associated protein 5, MDA-5, Murabutide down-regulated protein, RIG-I-like receptor 2, RLR-2, RNA helicase-DEAD box protein 116, IFIH1, MDA5, RH116, Hlcd, IDDM19. | |
| Introduction | |
| IFIH1 is a DEAD box protein which is upregulated in response to treatment with beta-interferon and a protein kinase C-activating compound, mezerein. Irreversible reprogramming of melanomas can be attained by therapy with both these agents; treatment with either agent alone only achieves reversible differentiation. DEAD box proteins are implicated in several cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. | |
| Source | |
| Sf9 Insect Cells. | |
| Physical Appearance | |
| Sterile Filtered clear solution. | |
| Formulation | |
| IFIH1 is supplied in 20mM HEPES buffer pH-7.9, 550mM NaCl and 6M Urea. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 93.0% as determined by SDS-PAGE. | |
| Precautions | |
| IFI30 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P13284 ) | |
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ADMEbio Team
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ADMEbio Team
