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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| CYK0189-2 | 7 days | 2 µg | $120.00 |
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| CYK0189-10 | 7 days | 10 µg | $290.00 | |||
| CYK0189-1 | 7 days | 1 mg | $8,320.00 |
Product Overview | |
| Name | IFN a 2b Human, 20 kd PEG |
|---|---|
| Description | |
| Interferon-alpha 2b 20kd-Pegylated Human Recombinant | |
| Accession (Primary) | Q86UP4 |
| Synonyms | |
| Interferon alpha 2b, IFNA, INFA2, IFN-? 2b, MGC125764, MGC125765. | |
| Introduction | |
| IFN-alpha is produced by macrophages and has antiviral activities. Interferon stimulates the production of two enzymes: protein kinase and an oligoadenylate synthetase. | |
| Source | |
| Saccharomyces cerevisiae. | |
| Physical Appearance | |
| Sterile Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| Lyophilized from a 0.2 µm filtered concentrated solution in PBS, pH-7.4 and 0.02% Tween-20. | |
| Stability | |
| Lyophilized glycosilated IFN-a 2b although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IFN-alpha 2b should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 98.0% as determined by(a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. | |
| Amino acid sequence | |
| CDLPQTHSLG SRRTLMLLAQ MRRISLFSCL KDRHDFGFPQ EEFGNQFQKA ETIPVLHEMI QQIFNLFSTK DSSAAWDETL LDKFYTELYQ QLNDLEACVI QGVGVTETPL MKEDSILAVR KYFQRITLYL KEKKYSPCAW EVVRAEIMRS FSLSTNLQES LRSKE. | |
| Biological Activity | |
| The specific activity as determined by an anti-viral assay was found to be no less than 1.6 x10 8 IU/mg. | |
| Solubility | |
| It is recommended to reconstitute the lyophilized glycosilated IFN alpha 2b in sterile 18MΩ-cm H2O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. | |
| Precautions | |
| IFN a 2b Human, 20 kd PEG is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q86UP4 ) | |
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ADMEbio Team
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