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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| CYK0191-5 | 7 days | 5 µg | $120.00 |
Select product before adding to cart
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| CYK0191-20 | 7 days | 20 µg | $290.00 | |||
| CYK0191-1 | 7 days | 1 mg | $5,616.00 |
Product Overview | |
| Name | IFN b 1a Human |
|---|---|
| Description | |
| IFN-Beta 1a Human Recombinant | |
| Accession (Primary) | P01574 |
| Synonyms | |
| Leukocyte IFN, B cell IFN, Type I IFN, IFNB1, IFB, IFF, IFNB, IFN-b 1b, MGC96956. | |
| Introduction | |
| IFN-beta 1b has antiviral, antibacterial and anticancer activities. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| Lyophilized from 1mg/ml solution containing 50mg Human Albumin & 50mg dextrose. | |
| Stability | |
| Lyophilized IFN-beta 1b although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IFNB 1b should be stored at 4°C between 2-7 days and for future use below -18°C. Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 98.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. | |
| Amino acid sequence | |
| The sequence of the first five N-terminal amino acids was determined and was found to be Ser-Tyr-Asn-Leu-Leu. | |
| Biological Activity | |
| The specific activity as determined in a viral resistance assay (human "Wish" cell line and VSV virus or the monkey VERO cell line with EMCV virus) was found to be 32 x 10 6 IU/mg. | |
| Solubility | |
| It is recommended to reconstitute the lyophilized IFN beta-1b in sterile 18M-cm H2O at a concentration of 0.25mg/ml, which can then be further diluted to other aqueous solutions. | |
| Protein content | |
| Protein quantitation was carried out by two independent methods: 1. UV spectroscopy at 280 nm using the absorbency value of 1.493 as the extinction coefficient for a 0.1% (1mg/ml) solution. This value is calculated by the PC GENE computer analysis program of protein sequences (IntelliGenetics). 2. Analysis by RP-HPLC, using a calibrated solution of IFN-beta as a Reference Standard. | |
| Precautions | |
| IFN b 1a Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P01574 ) | |
References |
Title :IFNG induces apoptosis in human SH-SY5Y neuroblastoma cells through activation of JAK–STAT signaling and down-regulation of PI3K/Akt pathway. Publication :Article first published online: 11 NOV 2010 DOI:10.1111/j.1471-4159.2010.07046.x Link : IFN b 1a prospec publication |
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ADMEbio Team
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