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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| CYK0196-10 | 7 days | 10 µg | $120.00 |
Select product before adding to cart
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| CYK0196-50 | 7 days | 50 µg | $290.00 | |||
| CYK0196-1 | 7 days | 1 mg | $3,520.00 |
Product Overview | |
| Name | IFN g Human, His |
|---|---|
| Description | |
| Interferon-Gamma Human Recombinant, His Tag | |
| Accession (Primary) | P01579 |
| Synonyms | |
| Immune IFN, type II IFN, T cell IFN, MAF, IFNG, IFG, IFI, IFN-gamma. | |
| Introduction | |
| IFN-gamma produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions, it is a potent activator of macrophages, and has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I IFNs. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| Lyophilized from a 0.2 µm filtered concentrated (1mg/ml) solution in PBS, pH 7.4 and 5% trehalose. | |
| Stability | |
| Lyophilized IFN-gamma although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IFN-gamma should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. | |
| Amino acid sequence | |
| MHGTVIESLE SLNNYFNSSG IDVEEKSLFL DIWRNWQKDG DMKILQSQII SFYLRLFEVL KDNQAISNNI SVIESHLITT FFSNSKAKKD AFMSIAKFEV NNPQVQRQAF NELIRVVHQL LPESSLRKRK RSRC. | |
| Biological Activity | |
| The specific activity as determined in a viral resistance assay is < 0.1 ng/ml, corresponding to a specific activity of 10,000,000 IU/mg | |
| Solubility | |
| It is recommended to reconstitute the lyophilized IFN-gamma in sterile distilled water or 20mM AcOH at concentrations ranging between 0.1mg-0.5mg/ml, which can then be further diluted to other aqueous solutions. | |
| References | |
| Title:IFN-γ and interleukin-4 reciprocally regulate CD8 expression in CD8 + T cells. Publication:Published online before print November 6, 2008, doi: 10.1073/pnas.0809549105 PNAS November 11, 2008 vol. 105 no. 45 17475-17480 Link: IFN g Mouse prospec publication | |
| Precautions | |
| IFN g Human, His is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P01579 ) | |
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ADMEbio Team
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