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IFN g Mouse

IFN-Gamma Mouse Recombinant

 
Catalog #
CYK0197
Uniprot Id
P01580
 
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 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
CYK0197-20 7 days 20 µg $120.00
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CYK0197-100 7 days 100 µg $290.00
CYK0197-1 7 days 1 mg $1,584.00
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Product Overview

NameIFN g Mouse
Description
IFN-Gamma Mouse Recombinant
Accession (Primary)P01580
Synonyms
Immune IFN, type II IFN, T cell IFN, MAF, IFNG, IFG, IFI, IFN-gamma.
Introduction
IFN-gamma produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions, it is a potent activator of macrophages, and has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I IFNs.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation
Lyophilized from a 0.2 µm filtered concentrated (1mg/ml) solution in PBS, pH 7.4.
Stability
Lyophilized IFN-gamma although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IFN-gamma should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Purity
Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Amino acid sequence
The sequence of the first five N-terminal amino acids was determined and was found to be Met-Gln-Gly-Tyr-Leu.
Biological Activity
The specific activity as determined by the cytopathic affect inhibition assay with murine L929 cells chalenged with EMC virus was < 0.1 ng/ml, corresponding to a specific activity of 10,000,000units/mg.
Solubility
It is recommended to reconstitute the lyophilized IFN-gamma in sterile 18MΩ-cm H2O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.
Precautions
IFN g Mouse is for research use only and not for use in diagnostic or therapeutic procedures.

Target Information: ( P01580 )

References

Title:IFN-γ and interleukin-4 reciprocally regulate CD8 expression in CD8 + T cells. Publication:Published online before print November 6, 2008, doi: 10.1073/pnas.0809549105 PNAS November 11, 2008 vol. 105 no. 45 17475-17480 Link: IFN g Mouse prospec publication

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