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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| CYK0201-5 | 7 days | 5 µg | $120.00 |
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| CYK0201-20 | 7 days | 20 µg | $290.00 | |||
| CYK0201-1 | 7 days | 1 mg | $4,320.00 |
Product Overview | |
| Name | IFNA14 Human |
|---|---|
| Description | |
| Interferon-alpha 14 Human Recombinant | |
| Accession (Primary) | P01570 |
| Synonyms | |
| IFN-alpha 1a, IFN-a 1a, IFN alpha 1a. | |
| Introduction | |
| At least 23 different variants of IFN-alpha are known. The individual proteins have molecular masses between 19-26 kDa and consist of proteins with lengths of 156-166 and 172 amino acids. All IFN-alpha subtypes possess a common conserved sequence region between amino acid positions 115-151 while the amino-terminal ends are variable. Many IFN-alpha subtypes differ in their sequences at only one or two positions. Naturally occurring variants also include proteins truncated by 10 amino acids at the carboxy-terminal end. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| The IFN-a 1a protein was lyophilized from a 0.2 µm filtered concentrated solution in PBS, pH 7.4, containing 3% Mannitol, 5% Trehalose, 0.05% Tween-80. | |
| Stability | |
| Lyophilized IFNA1A although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IFN-alpha 1a should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 97.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. | |
| Amino acid sequence | |
| MCDLPETHSL DNRRTLMLLA QMSRISPSSC LMDRHDFGFP QEEFDGNQFQ KAPAISVLHE LIQQIFNLFT TKDSSAAWDE DLLDKFCTEL YQQLNDLEAC VMQEERVGET PLMN A DSILA VKKYFRRITL YLTEKKYSPC AWEVVRAEIM RSLSLSTNLQ ERLRRKE. | |
| Biological Activity | |
| The specific activity as determined in a viral resistance assay viral ressistance assay was found to be 100,000,000IU/ mg. | |
| Solubility | |
| It is recommended to reconstitute the lyophilized IFN alpha 1a in sterile 18MΩ-cm H2O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. | |
| Precautions | |
| IFNA14 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P01570 ) | |
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ADMEbio Team
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ADMEbio Team
