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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| CYK0208-2 | 7 days | 2 µg | $120.00 |
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| CYK0208-10 | 7 days | 10 µg | $290.00 | |||
| CYK0208-1 | 7 days | 1 mg | $8,320.00 |
Product Overview | |
| Name | IFNG 139 a.a. Human |
|---|---|
| Description | |
| Interferon-gamma 139 a.a Human Recombinant | |
| Accession (Primary) | P01579 |
| Synonyms | |
| Immune Interferon, type II interferon, T cell interferon, MAF, IFNG, IFG, IFI, IFN-gamma. | |
| Introduction | |
| IFN-gamma produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions, it is a potent activator of macrophages, and has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| The IFNG was lyophilized from a 0.2 µm filtered concentrated solution in 25mM Sodium Succinate, pH 5.0, 60mM NaCl, with 0.1% Tween-80. | |
| Stability | |
| Lyophilized IFNG although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IFNG should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 97.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. | |
| Amino acid sequence | |
| QAMFFKEIEN LKEYFNASNP DVSDGGSLFV DILKKWREES DKTIIQSQIV SFYLKLFDNF KDNQIIQRSM DTIKEDMLGK FLNSSTSKRE DFLKLIQIPV NDLQVQRKAI NELIKVMNDL SPRSNLRKRK RSQNLFRGRR ASK | |
| Biological Activity | |
| The ED50 as determined by an anti-viral assay using A-72 canine fibroma cells infected with vesicular stomatitis virus (VSV) is less than 2.0 ng/ml, corresponding to a specific activity of > 5.0 × 10 5 IU/mg. | |
| Solubility | |
| It is recommended to reconstitute the lyophilized IFNG in sterile distilled H2O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. | |
| Precautions | |
| IFNG 139 a.a. Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P01579 ) | |
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ADMEbio Team
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ADMEbio Team
