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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| CYK0236-2 | 7 days | 2 µg | $120.00 |
Select product before adding to cart
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| CYK0236-10 | 7 days | 10 µg | $290.00 | |||
| CYK0236-1 | 7 days | 1 mg | $7,488.00 |
Product Overview | |
| Name | IL 1 beta Rat |
|---|---|
| Description | |
| Interleukin-1 beta Rat Recombinant | |
| Accession (Primary) | Q63264 |
| Immunogen | |
| r.Human IL-10. | |
| Synonyms | |
| B-TCGF, CSIF, TGIF, IL-10, IL10A, MGC126450, MGC126451, Cytokine synthesis inhibitory factor. | |
| Introduction | |
| IL10 is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. | |
| Formulation | |
| 1mg/ml in PBS (after reconstitution). | |
| Solubility | |
| Reconstitute with sterile H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. | |
| Type | |
| Mouse Anti Human Monoclonal. | |
| Clone | |
| NYR-HIL10. | |
| Ig Subclass | |
| Mouse IgG1. | |
| Purification Method | |
| Ion excahnge. | |
| Storage Procedures | |
| In lyophilized form, for long periods, store at 4oC in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20oC. | |
| Shipping Conditions | |
| Antibody is shipped lyophilized at ambient temperature. | |
| Titer | |
| By direct ELISA, 1:20,000 dilution will yield >1.0 O.D using alkaline phosphatase conjugated rabbit anti-mouse Ig (Jackson Laboratories). | |
| Precautions | |
| IL 1 beta Rat is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q63264 ) | |
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Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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ADMEbio Team
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ADMEbio Team
