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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| CYK0242-2 | 7 days | 2 µg | $120.00 |
Select product before adding to cart
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| CYK0242-10 | 7 days | 10 µg | $290.00 | |||
| CYK0242-1 | 7 days | 1 mg | $7,488.00 |
Product Overview | |
| Name | IL 11 Mouse |
|---|---|
| Description | |
| Interleukin-11 Mouse Recombinant | |
| Accession (Primary) | P47873 |
| Synonyms | |
| NKSF, CTL maturation factor (TCMF), Cytotoxic lymphocyte maturation factor (CLMF), TSF, Edodekin-alpha, IL-12. | |
| Introduction | |
| IL-12 is a heterodimeric cytokine that stimulates the production of IFNgamma from T-cells and natural killer cells, and also induces differentiation of Th1 helper cells. It is an initiator of cell-mediated immunity. | |
| Source | |
| HEK-293 Cells. | |
| Physical Appearance | |
| Sterile Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| The protein was lyophilized from 0.5xPBS, pH 7.5. | |
| Stability | |
| Lyophilized mouse IL-12 although stable at room temperature for 3 weeks, should be stored below -18°C. Upon reconstitution IL12 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 95% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| p35 Subunit: RVIPVSGPAR CLSQSRNLLK TTDDMVKTAR EKLKHYSCTA EDIDHEDITR DQTSTLKTCL PLELHKNESC LATRETSSTT RGSCLPPQKT SLMMTLCLGS IYEDLKMYQT EFQAINAALQ NHNHQQIILD KGMLVAIDEL MQSLNHNGET LRQKPPVGEA DPYRVKMKLC ILLHAFSTRV VTINRVMGYL SSA. p40 Subunit: MWELEKDVYV VEVDWTPDAP GETVNLTCDT PEEDDITWTS DQRHGVIGSG KTLTITVKEF LDAGQYTCHK GGETLSHSHL LLHKKENGIW STEILKNFKN KTFLKCEAPN YSGRFTCSWL VQRNMDLKFN IKSSSSSPDS RAVTCGMASL SAEKVTLDQR DYEKYSVSCQ EDVTCPTAEE TLPIELALEA RQQNKYENYS TSFFIRDIIK PDPPKNLQMK PLKNSQVEVS WEYPDSWSTP HSYFSLKFFV RIQRKKEKMK ETEEGCNQKG AFLVEKTSTE VQCKGGNVCV QAQDRYYNSS CSKWACVPCR VRS. | |
| Biological Activity | |
| IL-12 Mouse has full biological activity when compared to standards. The ED 50 is determined by the dose-dependent induces secretion of SEAP in HEK-Blue IL-12 cells is 2.302 ng/ml corresponding to a specific activity of 4.3x10 5 units/mg. | |
| Solubility | |
| It is recommended to reconstitute the lyophilized murine IL12 in sterile distilled pyrogen free water at 100 µg/ml, which can then be further diluted to other aqueous solutions. | |
| Precautions | |
| IL 11 Mouse is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P47873 ) | |
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ADMEbio Team
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