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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| CYK0253-2 | 7 days | 2 µg | $120.00 |
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| CYK0253-10 | 7 days | 10 µg | $290.00 | |||
| CYK0253-1 | 7 days | 1 mg | $7,488.00 |
Product Overview | |
| Name | IL 13 Variant Human |
|---|---|
| Description | |
| Interleukin-13 Variant Human Recombinant | |
| Accession (Primary) | P35225 |
| Immunogen | |
| r.Human IL-15. | |
| Synonyms | |
| IL-15, MGC9721. | |
| Introduction | |
| The protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Two alternatively spliced transcript variants of this gene encoding the same protein have been reported. | |
| Formulation | |
| 1mg/ml in PBS (after reconstitution). | |
| Solubility | |
| Reconstitute with sterile H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. | |
| Applications | |
| Direct ELISA, Immuneprecipitation, Immunohistochemistry. | |
| Type | |
| Mouse Anti Human Monoclonal. | |
| Clone | |
| YNR-HIL15. | |
| Ig Subclass | |
| Mouse IgG1. | |
| Purification Method | |
| Ion exchange. | |
| Storage Procedures | |
| In lyophilized form, for long periods, store at 4oC in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20oC. | |
| Shipping Conditions | |
| Antibody is shipped lyophilized at ambient temperature. | |
| Titer | |
| By direct ELISA, 1:20,000 dilution will yield >1.0 O.D using alkaline phosphatase conjugated rabbit anti-mouse Ig (Jackson Laboratories). | |
| Precautions | |
| IL 13 Variant Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P35225 ) | |
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ADMEbio Team
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ADMEbio Team
