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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| CYK0259-2 | 7 days | 2 µg | $120.00 |
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| CYK0259-10 | 7 days | 10 µg | $290.00 | |||
| CYK0259-1 | 7 days | 1 mg | $7,488.00 |
Product Overview | |
| Name | IL 16 Human, (130 a.a.) |
|---|---|
| Description | |
| Interleukin-16 Human Recombinant, (130 a.a.) | |
| Accession (Primary) | Q14005 |
| Synonyms | |
| IL16, Interleukin-16, LCF, Lymphocyte Chemoattractant Factor, prIL-16, IL-16, FLJ16806, FLJ42735, FLJ44234, HsT19289. | |
| Introduction | |
| IL-16 is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of IL-16 is mediated by CD4. The product of this gene undergoes proteolytic processing, which is found to yield two functional proteins. IL-16 functions exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control. Caspase 3 is reported to be involved in the proteolytic processing of this protein. Two transcript variants encoding different isoforms have been found for this gene. IL-16 stimulates a migratory response in cd4+ lymphocytes, monocytes, and eosinophils. Also induces t-lymphocyte expression of interleukin 2 receptor, ligand for cd4. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered solution. | |
| Formulation | |
| IL-16 His tag protein (1mg/ml) contains 20mM Tris-HCl pH-8, 1mM PMSF & 10% glycerol. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles. | |
| Purity | |
| Greater than 95.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| MGSSHHHHHH SSGLVPRGSH MPDLNSSTDS AASASAASDV SVESTAEATV CTVTLEKMSAGLGFSLEGGK GSLHGDKPLT INRIFKGAAS EQSETVQPGD EILQLGGTAM QGLTRFEAWN IIKALPDGPV TIVIRRKSLQ SKETTAAGDS. | |
| Precautions | |
| IL 16 Human, (130 a.a.) is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q14005 ) | |
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