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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| CYK0293-2 | 7 days | 2 µg | $120.00 |
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| CYK0293-10 | 7 days | 10 µg | $290.00 | |||
| CYK0293-1 | 7 days | 1 mg | $7,488.00 |
Product Overview | |
| Name | IL 2 Porcine |
|---|---|
| Description | |
| Interleukin-2 Porcine Recombinant | |
| Accession (Primary) | P26891 |
| Synonyms | |
| T-cell growth factor (TCGF), Interleukin-2, Lymphokine, IL-2. | |
| Introduction | |
| IL2 is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile filtered colorless solution. | |
| Formulation | |
| The IL-2 solution contains 0.2 µm filtered solution in 20mM PB pH3.5 and 30% Glycerol. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 97.0% as determined by SDS-PAGE and HPLC. | |
| Amino acid sequence | |
| APTSSPAKET QQHLEQLLLD LQVLLRGIDN YKNLKLPMML TFKFYLPKQA TELKHLQCLE NELGALQRVL DLTQSKSFHL EDAGNFISNI RVTVVKLKGS ENKFECQFDD EPATVVEFLR RWIAICQSII STMTQ. | |
| Biological Activity | |
| The ED 50 as determined by the dose-dependant stimulation of murine CTLL-2 cells is less than 0.2ng/ml, corresponding to a Specific Activity of 5,000,000IU/mg. | |
| References | |
| Title :Functional Gap Junctions Facilitate Melanoma Antigen Transfer and Cross-Presentation between Human Dendritic Cells. Publication :The Journal of Immunology June 1, 2007 vol. 178 no. 11 6949-6957 Link : IL 2 Rat prospec publication | |
| Precautions | |
| IL 2 Porcine is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P26891 ) | |
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ADMEbio Team
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