| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| CYK0328-5 | 7 days | 5 µg | $120.00 |
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| CYK0328-20 | 7 days | 20 µg | $290.00 | |||
| CYK0328-1 | 7 days | 1 mg | $4,320.00 |
Product Overview | |
| Name | IL 33 Rat, His |
|---|---|
| Description | |
| Interleukin-33 Rat Recombinant, His Tag | |
| Accession (Primary) | Q66H70 |
| Immunogen | |
| r.Murine IL-4. | |
| Synonyms | |
| BCGF, BCDF, B cell stimulating factor, BSF-1, Lymphocyte stimulatory factor 1, IL-4, MGC79402, Binetrakin, Pitrakinra. | |
| Introduction | |
| IL4 is a pleiotropic cytokine produced by activated T cells. IL4 is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. IL4, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. | |
| Formulation | |
| 1mg/ml in PBS (after reconstitution). | |
| Solubility | |
| Reconstitute with sterile H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. | |
| Applications | |
| Direct ELISA, Western Blot, Immuneprecipitation, Immunohistochemistry, Intracellular staining. | |
| Type | |
| Rat Anti Mouse Monoclonal. | |
| Clone | |
| NYRmIL-4. | |
| Ig Subclass | |
| Rat IgG1. | |
| Purification Method | |
| Ion exchange. | |
| Storage Procedures | |
| In lyophilized form, for long periods, store at 4oC in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20oC. | |
| Shipping Conditions | |
| Antibody is shipped lyophilized at ambient temperature. | |
| Titer | |
| By direct ELISA, 1:5,000 dilution will yield 0.4 O.D using alkaline phosphatase conjugated rabbit anti-mouse Ig (Jackson Laboratories). | |
| Precautions | |
| IL 33 Rat, His is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q66H70 ) | |
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ADMEbio Team
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ADMEbio Team