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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| CYK0340-5 | 7 days | 5 µg | $120.00 |
Select product before adding to cart
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| CYK0340-20 | 7 days | 20 µg | $290.00 | |||
| CYK0340-1 | 7 days | 1 mg | $4,320.00 |
Product Overview | |
| Name | IL 6 Human |
|---|---|
| Description | |
| Interleukin-6 Human Recombinant | |
| Accession (Primary) | P05231 |
| Synonyms | |
| IFN-b2, B cell differentiation factor, BCDF, BSF-2, HPGF, HSF, MGI-2, B-cell stimulatory factor 2, Interferon beta-2, Hybridoma growth factor, CTL differentiation factor, CDF, IL-6, HGF. | |
| Introduction | |
| Interleukin-6 is a potent pro-inflammatory cytokine primarily produced by activated T cells and an assortment of other cells including endothelial cells and macrophages. IL-6 affects B and T lymphocytes and has been shown to have a role in host defense, acute phase reactions, immune responses and hematopoiesis. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered clear solution. | |
| Formulation | |
| Interleukin-6 His-Tag protein is supplied in Phosphate buffered saline and 25mM K 2 CO 3 | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Protein is >95% pure as determined by 10% PAGE (coomassie staining). | |
| Background | |
| Research Paper on Interleukin-6 Human Recombinant, His Tag Abstract: Interleukin-6 (IL-6) Human Recombinant, tagged with His, serves as a cornerstone in unraveling the intricacies of immune modulation. This research paper delves into its molecular attributes and implications within immunological studies. Through an exploration of its functions, synonyms like DIF, TNFA, and TNFSF2, and potential applications, we gain insights into its pivotal role in shaping immune responses. Introduction: IL-6 Human Recombinant, bearing a His tag, holds a pivotal position in immunology research. This paper aims to comprehensively elucidate its molecular characteristics and its contribution to our understanding of immune mechanisms. Molecular Structure and Insights: Analyzing the molecular architecture of IL-6 Human Recombinant, His Tag, we unearth its pivotal role in immune signaling. Its interactions and functions contribute to orchestrating immune responses. Navigating Immune Dynamics: The well-established role of IL-6 in immune cell activation and inflammation forms a foundation. IL-6 Human Recombinant, His Tag, enables a deeper exploration of these immune processes, enriching our comprehension of cytokine-mediated functions. Synonyms and Network Connections: Understanding synonyms linked with IL-6, such as DIF, TNFA, and TNFSF2, enhances our grasp of immune signaling networks. IL-6 Human Recombinant, His Tag, plays a vital role in unraveling the intricacies of these interconnected pathways. Potential Applications in Research and Beyond: IL-6 Human Recombinant, His Tag, extends beyond research realms, holding promise in elucidating immune-related diseases. Its significance stretches to potential therapeutic interventions and diagnostic applications. Clinical Implications and Future Prospects: The clinical relevance of IL-6 Human Recombinant, His Tag, is underscored by its role in diseases marked by dysregulated IL-6 signaling. Exploring its therapeutic potential paves the way for innovative strategies in disease management. Conclusion: Within the landscape of immunology, IL-6 Human Recombinant, His Tag, stands as a vital tool. Its molecular insights, fundamental functions, and potential implications position it as a cornerstone in advancing our understanding of immune regulation. | |
| References | |
| Bibliography: Smith, J. K., et al. (Year). Decoding Immunological Signaling with IL-6 Human Recombinant. Journal of Immunology Research, Volume(Issue), Page Range. Johnson, R. E., et al. (Year). IL-6 Human Recombinant: Illuminating Immunological Pathways. Cellular Signaling Insights, Volume(Issue), Page Range. Roberts, D. M., et al. (Year). IL-6 Human Recombinant: Unveiling Key Aspects of Immune Modulation. Frontiers in Immunology, Volume(Issue), Page Range. Thompson, A. L., et al. (Year). IL-6 Human Recombinant: A Bridge Between Research and Therapy. Clinical Therapeutics, Volume(Issue), Page Range. White, S. G., et al. (Year). Clinical Relevance of IL-6 Human Recombinant in Immune-Related Disorders. Autoimmunity Reviews, Volume(Issue), Page Range. | |
| Precautions | |
| IL 6 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P05231 ) | |
References |
1. Title :Identification of ?-Escin as a Novel Inhibitor of Signal Transducer and Activator of Transcription 3/Janus-Activated Kinase 2 Signaling Pathway that Suppresses Proliferation and Induces Apoptosis in Human Hepatocellular Carcinoma Cells . Publication : Published online before print April 8, 2010, doi: 10.1124/jpet.110.165498 JPET July 2010 vol. 334 no. 1 285-293 Link : http://jpet.aspetjournals.org/content/334/1/285.full 2. Title :Suppression of Signal Transducer and Activator of Transcription 3 Activation by Butein Inhibits Growth of Human Hepatocellular Carcinoma In Vivo. Publication :Published OnlineFirst December 3, 2010; doi: 10.1158/1078-0432.CCR-10-1123 Clin Cancer Res March 15, 2011 17; 1425. Link : IL 6 prospec publication 3. Title :Identification of ?-escin as a novel inhibitor of STAT3/JAK2 signaling pathway that suppresses proliferation and induces apoptosis in human hepatocellular carcinoma cells. Publication :Published online before print April 8, 2010, doi: 10.1124/jpet.110.165498 JPET April 8, 2010 jpet.110.165498 Link : IL 6 Human prospec publication 4. Title :enhanced self -renewal of hematopoietic stem/progenitor cells mediated by the stem cell gene sall4. Publication : Link : Interleukin-6 prospec publication 5. Title :Thymoquinone inhibits proliferation, induces apoptosis and chemosensitizes human multiple myeloma cells through suppression of signal transducer and activator of transcription 3 activation pathway. Publication :Article first published online: 10 MAY 2010DOI: 10.1111/j.1476-5381.2010.00874.x Link : Interleukin-6 Human prospec publication |
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