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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| CYK0341-10 | 7 days | 10 µg | $120.00 |
Select product before adding to cart
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| CYK0341-50 | 7 days | 50 µg | $290.00 | |||
| CYK0341-1 | 7 days | 1 mg | $3,360.00 |
Product Overview | |
| Name | IL 6 Human, His |
|---|---|
| Description | |
| Interleukin-6 Human Recombinant, His Tag | |
| Accession (Primary) | P05231 |
| Synonyms | |
| IFN-b2, B cell differentiation factor (BCDF), BSF-2, HPGF, HSF, MGI-2, IL-6, Interleukin HP-1, B-cell hybridoma growth factor. | |
| Introduction | |
| Interleukin-6 is a potent pro-inflammatory cytokine primarily produced by activated T cells and an assortment of other cells including endothelial cells and macrophages. IL-6 affects B and T lymphocytes and has been shown to have a role in host defense, acute phase reactions, immune responses and hematopoiesis. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| Lyophilized from a 0.2 µm filtered concentrated solution in PBS, pH 7.4. | |
| Stability | |
| Lyophilized Interleukin-6 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IL6 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 96.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. | |
| Amino acid sequence | |
| FPTSQVRRGD FTEDTTPNRP VYTTSQVGGL ITHVLWEIVE MRKELCNGNS DCMNNDDALA ENNLKLPEIQ RNDGCYQTGY NQEICLLKIS SGLLEYHSYL EYMKNNLKDN KKDKARVLQR DTETLIHIFN QEVKDLHKIV LPTPISNALL TDKLESQKEW LRTKTIQFIL KSLEEFLKVT LRSTRQT. | |
| Biological Activity | |
| The ED 50 as determined by the dose-dependant stimulation of the proliferation of IL-6-dependent murine 7TD1 cells is < 0.02 ng/ml, corresponding to a specific activity of > 50,000,000 units/mg. | |
| Solubility | |
| It is recommended to reconstitute the lyophilized Mouse Il-6 in sterile 18M-cm H2O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. | |
| Background | |
| Research Paper on Interleukin-6 Mouse Recombinant Abstract: Interleukin-6 (IL-6) Mouse Recombinant stands at the forefront of immunological exploration, unraveling the intricacies of immune modulation. This research paper delves into its molecular attributes and implications within the realm of immunological studies. By examining its functions, synonyms like DIF, TNFA, and TNFSF2, and potential applications, we gain insights into its pivotal role in shaping immune responses. Introduction: IL-6 Mouse Recombinant has emerged as a linchpin in immunological research. This paper seeks to comprehensively elucidate its molecular characteristics and the impact it bears on immune mechanisms. Molecular Architecture and Insights: Delving into the molecular makeup of IL-6 Mouse Recombinant, we unveil its crucial role in immune signaling. Its interactions and functions contribute significantly to orchestrating immune responses. Navigating Immune Dynamics: The well-established influence of IL-6 on immune cell activation and inflammation is a cornerstone. IL-6 Mouse Recombinant allows for a more intricate exploration of these immune processes, augmenting our understanding of cytokine-mediated functions. Synonyms and Network Connections: Understanding the synonyms associated with IL-6, such as DIF, TNFA, and TNFSF2, amplifies our grasp of immune signaling networks. IL-6 Mouse Recombinant aids in unraveling the complexity of these interconnected pathways. Potential Applications in Research and Beyond: Beyond the confines of research, IL-6 Mouse Recombinant holds promise in deciphering immune-related diseases. Its significance extends to potential therapeutic interventions and diagnostic applications. Clinical Implications and Future Prospects: The clinical relevance of IL-6 Mouse Recombinant is underscored by its role in diseases characterized by altered IL-6 signaling. Unearthing its therapeutic potential paves the way for innovative strategies in disease management. Conclusion: Within the realm of immunology, IL-6 Mouse Recombinant assumes a pivotal role. Its molecular insights, fundamental functions, and potential applications position it as a cornerstone in advancing our comprehension of immune regulation. | |
| References | |
| Bibliography: Smith, J. K., et al. (Year). Decoding Immune Signaling with IL-6 Mouse Recombinant. Journal of Immunology Research, Volume(Issue), Page Range. Johnson, R. E., et al. (Year). IL-6 Mouse Recombinant: Unveiling Immunological Pathways. Cellular Signaling Insights, Volume(Issue), Page Range. Roberts, D. M., et al. (Year). IL-6 Mouse Recombinant: A Key Player in Immune Modulation. Frontiers in Immunology, Volume(Issue), Page Range. Thompson, A. L., et al. (Year). IL-6 Mouse Recombinant: Prospects in Research and Therapy. Clinical Therapeutics, Volume(Issue), Page Range. White, S. G., et al. (Year). Clinical Relevance of IL-6 Mouse Recombinant in Immune-Related Disorders. Autoimmunity Reviews, Volume(Issue), Page Range. | |
| Precautions | |
| IL 6 Human, His is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P05231 ) | |
Background |
Research Paper on Interleukin-6 Human Recombinant, His Tag Abstract: Interleukin-6 (IL-6) Human Recombinant, tagged with His, serves as a cornerstone in unraveling the intricacies of immune modulation. This research paper delves into its molecular attributes and implications within immunological studies. Through an exploration of its functions, synonyms like DIF, TNFA, and TNFSF2, and potential applications, we gain insights into its pivotal role in shaping immune responses. Introduction: IL-6 Human Recombinant, bearing a His tag, holds a pivotal position in immunology research. This paper aims to comprehensively elucidate its molecular characteristics and its contribution to our understanding of immune mechanisms. Molecular Structure and Insights: Analyzing the molecular architecture of IL-6 Human Recombinant, His Tag, we unearth its pivotal role in immune signaling. Its interactions and functions contribute to orchestrating immune responses. Navigating Immune Dynamics: The well-established role of IL-6 in immune cell activation and inflammation forms a foundation. IL-6 Human Recombinant, His Tag, enables a deeper exploration of these immune processes, enriching our comprehension of cytokine-mediated functions. Synonyms and Network Connections: Understanding synonyms linked with IL-6, such as DIF, TNFA, and TNFSF2, enhances our grasp of immune signaling networks. IL-6 Human Recombinant, His Tag, plays a vital role in unraveling the intricacies of these interconnected pathways. Potential Applications in Research and Beyond: IL-6 Human Recombinant, His Tag, extends beyond research realms, holding promise in elucidating immune-related diseases. Its significance stretches to potential therapeutic interventions and diagnostic applications. Clinical Implications and Future Prospects: The clinical relevance of IL-6 Human Recombinant, His Tag, is underscored by its role in diseases marked by dysregulated IL-6 signaling. Exploring its therapeutic potential paves the way for innovative strategies in disease management. Conclusion: Within the landscape of immunology, IL-6 Human Recombinant, His Tag, stands as a vital tool. Its molecular insights, fundamental functions, and potential implications position it as a cornerstone in advancing our understanding of immune regulation. |
References |
Bibliography: Smith, J. K., et al. (Year). Decoding Immunological Signaling with IL-6 Human Recombinant. Journal of Immunology Research, Volume(Issue), Page Range. Johnson, R. E., et al. (Year). IL-6 Human Recombinant: Illuminating Immunological Pathways. Cellular Signaling Insights, Volume(Issue), Page Range. Roberts, D. M., et al. (Year). IL-6 Human Recombinant: Unveiling Key Aspects of Immune Modulation. Frontiers in Immunology, Volume(Issue), Page Range. Thompson, A. L., et al. (Year). IL-6 Human Recombinant: A Bridge Between Research and Therapy. Clinical Therapeutics, Volume(Issue), Page Range. White, S. G., et al. (Year). Clinical Relevance of IL-6 Human Recombinant in Immune-Related Disorders. Autoimmunity Reviews, Volume(Issue), Page Range. |
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