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IL 7 Human, Yeast

Interleukin-7 Human Recombinant, Yeast

 
Catalog #
CYK0349
Uniprot Id
P13232
 
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 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
CYK0349-2 7 days 2 µg $120.00
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CYK0349-10 7 days 10 µg $290.00
CYK0349-1 7 days 1 mg $7,488.00
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Product Overview

NameIL 7 Human, Yeast
Description
Interleukin-7 Human Recombinant, Yeast
Accession (Primary)P13232
Synonyms
Lymphopoietin 1 (LP-1), pre-B cell factor, IL-7.
Introduction
Interleukin-7 is a potent lymphoid cell growth factor produced primarily by stromal cells. IL-7 has been shown to support the proliferation and differentiation of pre B- and early T cells as well as displaying a biological effect on cells of NK and myeloid lineages.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation
Filtered (0.2 µm) and lyophilized from a concentrated (1mg/ml) solution in 1×PBS, pH7.4 and 2% trehalose.
Stability
Lyophilized Interleukin-7 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IL7 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Purity
Greater than 96.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Amino acid sequence
ECHIKDKEGK AYESVLMISI DELDKMTGTD SNCPNNEPNF FRKHVCDDTK EAAFLNRAAR KLKQFLKMNI SEEFNVHLLT VSQGTQTLVN CTSKEEKNVK EQKKNDACFL KRLLREIKTC WNKILKGSI.
Biological Activity
The ED 50 was determined by the dose-dependent stimulation of the proliferation of murine 2E8 cells is less than 0.2 ng/ml, corresponding to a specific activity of > 5.0×10 6 IU/mg.
Solubility
It is recommended to reconstitute the lyophilized Interleukin 7 in sterile 18MΩ-cm H2O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.
References
Title: Disruption of Bis Leads to the Deterioration of the Vascular Niche for Hematopoietic Stem Cells Publication: Stem Cells 28.2 (2010): 268-278. Link: IL 7 Mouse prospec publication
Precautions
IL 7 Human, Yeast is for research use only and not for use in diagnostic or therapeutic procedures.

Target Information: ( P13232 )

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