| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| CYK0393-1 | 7 days | 1 µg | $120.00 |
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| CYK0393-5 | 7 days | 5 µg | $290.00 | |||
| CYK0393-100 | 7 days | 100 µg | $1,920.00 |
Product Overview | |
| Name | IL18RAP Human |
|---|---|
| Description | |
| Interleukin 18 Receptor Accessory Protein Human Recombinant | |
| Accession (Primary) | O95256 |
| Synonyms | |
| Melanoma differentiation association like protein, MDA1, NG.1, ZMDA1, IL-10C, IL-19 | |
| Introduction | |
| IL19 is a cytokine that belongs to the IL10 cytokine subfamily. IL-19 is found to be preferentially expressed in monocytes. IL19 binds the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described. | |
| Source | |
| HEK293 cells. | |
| Physical Appearance | |
| Sterile filtered colorless solution. | |
| Formulation | |
| IL19 protein (0.5mg/ml) contains 10% glycerol and Phosphate-Buffered Saline (pH 7.4). | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 95.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| DGSHMLRRCL ISTDMHHIEE SFQEIKRAIQ AKDTFPNVTI LSTLETLQII KPLDVCCVTK NLLAFYVDRV FKDHQEPNPK ILRKISSIAN SFLYMQKTLR QCQEQRQCHC RQEATNATRV IHDNYDQLEV HAAAIKSLGE LDVFLAWINK NHEVMFSA HH HHHH | |
| Precautions | |
| IL18RAP Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( O95256 ) | |
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