| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| CYK0394-2 | 7 days | 2 µg | $120.00 |
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| CYK0394-10 | 7 days | 10 µg | $290.00 | |||
| CYK0394-100 | 7 days | 100 µg | $1,600.00 |
Product Overview | |
| Name | IL19 Human, HEK |
|---|---|
| Description | |
| Interleukin-19 Human Recombinant, HEK | |
| Accession (Primary) | Q9UHD0 |
| Synonyms | |
| interleukin 1 alpha, IL1A, interleukin-1 alpha precursor,BAF, Hematopoietin-1, IL1 alpha, IL1F1hematopoietin-1, LAF, LEM, preinterleukin 1 alpha, pro-interleukin-1-alpha. | |
| Introduction | |
| The cytokine IL-1 alpha or hematopoietin 1 is a member to the interleukin 1 family, encoded by the IL1A gene in humans. Essentially Il-1 is in charge of inflammation and the rising of fever and sepsis. In order to disturb the mentioned processes and treatment for diseases, inhibitors for Interleukin 1 alpha are being developed. Neutrophils and macrophages are the main activators of IL-1 alpha, as well as endothelial and epithelial cells. By binding to the il1 receptor it is a major part in the immune response regulation. In the activation process of tumor necrosis factor-alpha the IL1A has a part as well, and has physiological, metabolic and hematopoietic activities. | |
| Source | |
| Sf9, Baculovirus cells . | |
| Physical Appearance | |
| Sterile Filtered colorless solution. | |
| Formulation | |
| IL1A protein solution (0.25mg/ml) containing Phosphate-Buffered Saline (pH7.4) and 10% glycerol. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 90.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| ADP SVAYNFH NNEKYNYIRI IKSQFILNDN LNQSIVRQTG GNYLMTAALQ NLDDAVKFDM GAYTSEDSKL PVTLRISKTR LFVSAQNEDE PVLLKEMPET PKTIRDETNL LFFWERHGSK HYFKSVAQPK LFIATQERKL VHMARGQPSI TDFRLLETQP HHHHHH | |
| Biological Activity | |
| Measured in a cell proliferation assay using D10.G4.1 mouse helper T cell. The ED50 range ≤ 2 ng/ml. | |
| Precautions | |
| IL19 Human, HEK is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q9UHD0 ) | |
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ADMEbio Team
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