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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| CYK0409-50 | 7 days | 50 µg | $1,200.00 |
Select product before adding to cart
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| CYK0409-100 | 7 days | 100 µg | $1,800.00 | |||
| CYK0409-1 | 7 days | 1 mg | $6,720.00 |
Product Overview | |
| Name | IL-2 Canine |
|---|---|
| Description | |
| Interleukin-2 Canine Recombinant | |
| Accession (Primary) | Q29416 |
| Synonyms | |
| Interleukin-2, IL-2, T-cell growth factor, TCGF. | |
| Introduction | |
| IL2 is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile filtered colorless solution. | |
| Formulation | |
| IL2 Canine protein solution (0. 5mg/ml) contains Phosphate buffered saline (pH7.4). | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles. | |
| Purity | |
| Greater than 95.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| MGSSHHHHHH SSGLVPRGSH MGSHM APITS SSTKETEQQM EQLLLDLQLL LNGVNNYENP QLSRMLTFKF YTPKKATEFT HLQCLAEELK NLEEVLGLPQ SKNVHLTDTK ELISNMNVTL LKLKGSETSY NCEYDDETAT ITEFLNKWIT FSQSIFSTLT. | |
| Biological Activity | |
| The ED50 measured in a cell proliferation assay using CTLL-2 mouse cytotoxic T cells. is < 0.3 ng/ml. | |
| Precautions | |
| IL-2 Canine is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q29416 ) | |
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ADMEbio Team
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ADMEbio Team
