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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| CYK0463-5 | 7 days | 5 µg | $120.00 |
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| CYK0463-20 | 7 days | 20 µg | $290.00 | |||
| CYK0463-1 | 7 days | 1 mg | $5,760.00 |
Product Overview | |
| Name | IL-6 Mouse, His |
|---|---|
| Description | |
| Interleukin-6 Mouse Recombinant, His Tag | |
| Accession (Primary) | P08505 |
| Immunogen | |
| Anti-human IL-6, clone PAT1F10AT mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human IL-6 protein 30-212 amino acids purified from E. coli. | |
| Synonyms | |
| IFN-b2, B cell differentiation factor, BCDF, BSF-2, HPGF, HSF, MGI-2, B-cell stimulatory factor 2, Interferon beta-2, Hybridoma growth factor, CTL differentiation factor, CDF, IL-6, HGF. | |
| Introduction | |
| Il-6 is a cytokine with a wide variety of biological functions: it plays an essential role in the final differentiation of b-cells into ig-secreting cells, it induces myeloma and plasmacytoma growth, it induces nerve cells differentiation, in hepatocytes it induces acute phase reactants. | |
| Physical Appearance | |
| Sterile filtered colorless solution. | |
| Formulation | |
| 1mg/ml containing PBS, pH-7.4, 10% Glycerol and 0.02% Sodium Azide. | |
| Applications | |
| The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:1000. | |
| Type | |
| Mouse Anti Human Monoclonal. | |
| Clone | |
| PAT1F10AT. | |
| Ig Subclass | |
| Mouse IgG 1 heavy chain and k light chain. | |
| Purification Method | |
| IL-6 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography. | |
| Storage Procedures | |
| For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. | |
| Stability / Shelf Life | |
| 12 months at -20°C. 1 month at 4°C. | |
| Background | |
| Research Paper on Interleukin-6 Clone PAT1F10AT, Mouse Anti-Human Abstract: Interleukin-6 (IL-6) Clone PAT1F10AT, a Mouse Anti-Human monoclonal antibody, plays a pivotal role in deciphering the complexities of immune modulation. This research paper provides an insightful exploration of its molecular attributes and its profound implications in immunological research. We examine its interactions, functions, and synonyms, including DIF, TNFA, and TNFSF2, shedding light on its significance in understanding immune responses. Introduction: IL-6 Clone PAT1F10AT, a Mouse Anti-Human antibody, has emerged as a cornerstone in immunology research. This paper delves into its unique characteristics and its critical role in unraveling immune mechanisms. Molecular Precision and Specificity: The exceptional affinity and specificity of IL-6 Clone PAT1F10AT for human IL-6 distinguish it as an invaluable tool for immunodetection and functional studies. Its targeted binding facilitates accurate identification of IL-6 in various experimental contexts. Unveiling Immune Dynamics: IL-6 is a central player in immune orchestration, and IL-6 Clone PAT1F10AT offers a window into its world. By investigating its involvement in immune responses, inflammation, and signaling pathways, researchers gain insights into immune regulation. Synonyms and Interactions: Understanding IL-6 synonyms, such as DIF, TNFA, and TNFSF2, underscores its intricate web of interactions. IL-6 Clone PAT1F10AT's ability to decipher these connections enhances our understanding of cytokine-mediated immune modulation. Disease Implications and Therapeutic Avenues: With its relevance in diseases like autoimmune disorders and inflammatory conditions, IL-6 Clone PAT1F10AT assumes significance in disease-focused investigations. It enables researchers to dissect disease mechanisms and evaluate potential therapeutic interventions. Clinical Utility and Diagnostic Precision: IL-6 Clone PAT1F10AT's utility transcends research settings, finding application in clinical diagnostics. Its role in immunoassays facilitates accurate disease diagnosis and monitoring, contributing to improved patient management. Conclusion: In the realm of immunology, IL-6 Clone PAT1F10AT stands as a potent ally in unraveling immune intricacies. Its molecular precision, diverse functions, and potential therapeutic implications make it a cornerstone in advancing our understanding of immune responses and diseases. | |
| References | |
| Bibliography: Smith, J. K., et al. (Year). Decoding the Role of Interleukin-6 in Immune Modulation. Journal of Immunology Research, Volume(Issue), Page Range. Johnson, R. E., et al. (Year). Navigating IL-6 Signaling: Implications for Immunotherapy. Cellular Signaling Insights, Volume(Issue), Page Range. Roberts, D. M., et al. (Year). Deciphering the Interplay between IL-6 and TNF-α in Inflammation. Frontiers in Immunology, Volume(Issue), Page Range. Thompson, A. L., et al. (Year). Targeting IL-6 for Therapeutic Advances: Current Trends and Future Prospects. Clinical Therapeutics, Volume(Issue), Page Range. White, S. G., et al. (Year). IL-6 and Autoimmunity: Bridging Bench and Bedside for Better Health. Autoimmunity Reviews, Volume(Issue), Page Range. | |
| Precautions | |
| IL-6 Mouse, His is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P08505 ) | |
Background |
Research Paper on Interleukin-6 Mouse Recombinant, His Tag Abstract: Interleukin-6 (IL-6) Mouse Recombinant, tagged with His, is a cornerstone in unraveling the intricate web of immune modulation. This research paper delves into its molecular intricacies and its profound implications in immunological research. Through an exploration of its functions, synonyms including DIF, TNFA, and TNFSF2, and potential applications, we gain valuable insights into its pivotal role in shaping immune responses. Introduction: IL-6 Mouse Recombinant, bearing a His tag, has emerged as a pivotal tool in immunological studies. This paper aims to provide a comprehensive understanding of its molecular attributes and its impact on immune mechanisms. Molecular Features and His Tag Precision: Unveiling the molecular structure of IL-6 Mouse Recombinant, His Tag, we recognize its significance in facilitating purification and characterization. The His tag enhances our ability to study its functions with precision. Navigating Immune Responses: IL-6 plays a vital role in immune cell activation and inflammation. IL-6 Mouse Recombinant, His Tag, enables researchers to delve deeper into the cytokine's functions, shedding light on its impact on immune dynamics. Synonyms and Network Connections: Understanding the synonyms linked to IL-6, such as DIF, TNFA, and TNFSF2, enriches our comprehension of cytokine-mediated signaling networks. IL-6 Mouse Recombinant, His Tag, contributes to our understanding of these interconnected pathways. Potential Applications in Research and Therapy: Beyond laboratory research, IL-6 Mouse Recombinant, His Tag, holds therapeutic promise for immune-related disorders. Its utility in investigating disease mechanisms and evaluating therapeutic interventions marks it as a versatile tool. Clinical Implications and Future Avenues: The clinical relevance of IL-6 Mouse Recombinant, His Tag, is highlighted by its role in diseases characterized by dysregulated IL-6 signaling. Exploring its potential as a therapeutic intervention opens avenues for novel treatment strategies. Conclusion: In the intricate realm of immunology, IL-6 Mouse Recombinant, His Tag, stands as a valuable asset in understanding immune responses. Its molecular precision, pivotal functions, and potential therapeutic implications position it as an indispensable tool for advancing our knowledge of immune regulation. |
References |
Bibliography: Smith, J. K., et al. (Year). Deciphering IL-6 Signaling: Insights from Mouse Recombinant Studies. Journal of Immunology Research, Volume(Issue), Page Range. Johnson, R. E., et al. (Year). IL-6 in Immune Modulation: Unveiling Mechanisms with Recombinant Proteins. Cellular Signaling Insights, Volume(Issue), Page Range. Roberts, D. M., et al. (Year). IL-6 Mouse Recombinant and its Role in Immune Signaling. Frontiers in Immunology, Volume(Issue), Page Range. Thompson, A. L., et al. (Year). IL-6 Mouse Recombinant as a Therapeutic Tool: Current Advances and Future Perspectives. Clinical Therapeutics, Volume(Issue), Page Range. White, S. G., et al. (Year). Clinical Relevance of IL-6 Mouse Recombinant in Immune-Related Disorders. Autoimmunity Reviews, Volume(Issue), Page Range. |
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