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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| CYK0469-2 | 7 days | 2 µg | $120.00 |
Select product before adding to cart
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| CYK0469-10 | 7 days | 10 µg | $290.00 | |||
| CYK0469-100 | 7 days | 100 µg | $1,920.00 |
Product Overview | |
| Name | IL-9 Human, Sf9 Active |
|---|---|
| Description | |
| Interleukin 9 Human Recombinant, Sf9, Active | |
| Accession (Primary) | P15248 |
| Synonyms | |
| Integrin-linked protein kinase, ILK-1, ILK-2, 59 kDa serine/threonine-protein kinase, p59ILK, ILK, ILK1, ILK2, DKFZp686F1765, P59. | |
| Introduction | |
| ILK1 (Integrin-linked kinase) is a serine/threonine protein kinase, containing 4 ankyrin-like repeats. ILK1 regulates a number of biological properties which include: anchorage-independent cell cycle progression, tumor cell invasion and apoptosis. ILK1 can also be implicated in mediating cell architecture, adhesion to integrin substrates and anchorage-dependent growth in epithelial cells. Furthermore, ILK1 phosphorylates beta-1 and beta-3 integrin subunit on serine and threonine residues, but also AKT1 and GSK3B. ILK1 interacts with the cytoplasmic domains of integrin ?1 and ?3 subunits in addition to several adaptors and signaling proteins, it also acts as a proximal receptor kinase regulating integrin-mediated signal transduction. ILK1 is a focal adhesion protein part of the complex ILK-PINCH. This complex is deemed to be one of the convergence points of integrin- and growth factor-signaling pathway. ILK1 is stimulated rapidly but briefly by both cell fibronectin interactions in a PI3-K-dependent manner, probably through the binding of PtdIns(3,4,5)P3 with a PH-like domain of ILK. ILK1 over-expression has been documented in a wide variety of human malignancies. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered clear solution. | |
| Formulation | |
| ILK1 protein is supplied in 25mM Sodium Acetate (pH 4.8) and 50% glycerol. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles. | |
| Purity | |
| Greater than 95.0% as determined by SDS-PAGE. | |
| Precautions | |
| IL-9 Human, Sf9 Active is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P15248 ) | |
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ADMEbio Team
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