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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| CYK0471-5 | 7 days | 5 µg | $120.00 |
Select product before adding to cart
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| CYK0471-20 | 7 days | 20 µg | $290.00 | |||
| CYK0471-1 | 7 days | 1 mg | $4,320.00 |
Product Overview | |
| Name | IRF 3 Human |
|---|---|
| Description | |
| IFN Regulatory Factor-3 Human Recombinant | |
| Accession (Primary) | Q14653 |
| Synonyms | |
| IFN Regulatory Factor 5, IRF-5, SLEB10, IBD14. | |
| Introduction | |
| IFN Regulatory Factor-5, also known as IRF5 belongs to the IFN regulatory factor (IRF) family, a group of transcription factors with various functions, including virus-mediated activation of IFN, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Multiple transcript variants encoding different isoforms have been found for this gene. In addition, IRF5 is implicated in the induction of IFNs IFNA and INFB and inflammatory cytokines upon virus infection. IRF5 is activated by TLR7 or TLR8 signaling. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered clear solution. | |
| Formulation | |
| IRF5 protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 30% glycerol and 1mM DTT. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please avoid freeze thaw cycles. | |
| Purity | |
| Greater than 85% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGS PPTL QPPTLQPPVV LGPPAPDPSP LAPPPGNPAG FRELLSEVLE PGPLPASLPP AGEQLLPDLL I | |
| Precautions | |
| IRF 3 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q14653 ) | |
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ADMEbio Team
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ADMEbio Team
