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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| CYK0502-5 | 7 days | 5 µg | $120.00 |
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| CYK0502-25 | 7 days | 25 µg | $290.00 | |||
| CYK0502-1 | 7 days | 1 mg | $4,320.00 |
Product Overview | |
| Name | RELM b Mouse |
|---|---|
| Description | |
| RELM-Beta Mouse Recombinant | |
| Accession (Primary) | Q99P86 |
| Synonyms | |
| Resistin-like gamma, RELMgamma,RELM-γ, RELM-g. | |
| Introduction | |
| RELM-gamma is a novel member of the resistin-like molecule/found in inflammatory zone (RELM/FIZZ) family in mice and rats. Microarray and real-time RT-PCR experiments revealed a repression of RELMgamma mRNA in nasal respiratory epithelium of cigarette smoke-exposed versus untreated rats. The analysis of the physiological tissue-specific expression revealed highest expression in hematopoietic tissues, suggesting a cytokine-like role for RELM-gamma. RELM-gamma-mRNA is detectable in bone marrow, spleen, and lung as well as in peripheral blood granulocytes. Promyelocytic HL60 cells transfected with a RELM-gamma expression plasmid have an increased proliferation rate compared to mock-transfected cells and display an altered response to retinoic acid-induced granulocytic differentiation. Taken together, these data provide the first experimental evidence that RELM-gamma is a secreted molecule with a restricted expression pattern that may play a role in promyelocytic differentiation. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| Lyophilized from a sterile filtered solution containing 0.1 % trifluoroacetic acid (TFA). | |
| Stability | |
| Lyophilized RELM g although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution RELM g Mouse should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 95.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| MEGTLESIVE KKVKELLANR DDCPSTVTKT FSCTSITASG RLASCPSGMT VTGCACGYGC GSWDIRDGNT CHCQCSTMDW ATARCCQLA. | |
| Solubility | |
| It is recommended to reconstitute the lyophilized RELM g in sterile 18MΩ-cm H 2 O at a concentration of 100 µg/ml, which can then be further diluted to other aqueous solutions. | |
| Precautions | |
| RELM b Mouse is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q99P86 ) | |
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ADMEbio Team
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ADMEbio Team
