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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| CYK0507-50 | 7 days | 50 µg | $400.00 |
Select product before adding to cart
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| CYK0507-100 | 7 days | 100 µg | $600.00 | |||
| CYK0507-1 | 7 days | 1 mg | $2,400.00 |
Product Overview | |
| Name | Resistin Human (64-110) |
|---|---|
| Description | |
| Resistin (64-110) Human Recombinant | |
| Accession (Primary) | Q9HD89 |
| Synonyms | |
| RETN,ADSF,FIZZ3,RETN1,RSTN,XCP1,resistin precursor, Adipose tissue-specific secretory factor, ADSFMGC126609, C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein, Cysteine-rich secreted protein A12-alpha-like 2, Cysteine-rich secreted protein FIZZ3, FIZZ3; FIZZ3MGC126603, found in inflammatory zone 3, HXCP1. | |
| Introduction | |
| Resistin, also known as adipose tissue-specific secretory factor (ADSF) is a cysteine-rich peptide derived from adipose tissue. Resistin takes part in the inflammatory response, glucose metabolism, and angiogenesis.Resistin blocks insulinstimulated uptake of glucose by adipocytes and promote glucose release by hepatocytes. As such,Resistin considered to participate in diet‑induced insulin-sensitivity. Resistin causes high levels of lowdensity lipoprotein (LDL), increasing the risk of heart disease. | |
| Source | |
| HEK293 cells. | |
| Physical Appearance | |
| Sterile Filtered colorless solution. | |
| Formulation | |
| Resistin protein (1mg/ml) contains 20% glycerol and 20mM Sodium citrate (pH3.0). | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 95.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| KTLCSMEEAI NERIQEVAGS LIFRAISSIG LECQSVTSRG DLATCPRGFA VTGCTCGSAC GSWDVRAETT CHCQCAGMDW TGARCCRVQP HHHHHH | |
| Precautions | |
| Resistin Human (64-110) is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q9HD89 ) | |
Background |
Human resistin is an adipokine primarily secreted by adipose tissue, mainly in response to obesity and inflammatory conditions. Resistin Function Resistin takes part in insulin resistance, which can be the cause of the development of type 2 diabetes. Resistin can also affect glucose metabolism and insulin signalling. Regulation Levels of resistin are influenced by factors such as inflammation, obesity and certain hormones. It tends to increase in conditions associated with obesity and metabolic syndrome. Clinical Relevance Elevated levels of resistin have been associated with obesity-related conditions, cardiovascular diseases, and metabolic disorders. Resisting is considered as a potential biomarker for these conditions. Resistin Mechanism Resistin promotes insulin resistance through different pathways such as the modulation of inflammatory processes and the inhibition of insulin signaling in target tissues like liver and muscle. Research Ongoing studies are exploring resistin’s role in metabolic regulation, the exact mechanisms of action of resistin and its potential as a therapeutic target for treating metabolic diseases. Overall, resistin is a critical factor in metabolic health, mainly in the context of diabetes and obesity. |
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