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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| CYK0542-5 | 7 days | 5 µg | $120.00 |
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| CYK0542-20 | 7 days | 20 µg | $290.00 | |||
| CYK0542-1 | 7 days | 1 mg | $4,640.00 |
Product Overview | |
| Name | TFF1 Human, His |
|---|---|
| Description | |
| Trefoil Factor-1 Human Recombinant, His Tag | |
| Accession (Primary) | P04155 |
| Synonyms | |
| TFF-2, Spasmolytic polypeptide, Spasmolysin, SML1, Trefoil factor 2, SP, TFF2. | |
| Introduction | |
| Proteins of the TFF family are characterized by obtaining a minimum of 1 copy of the trefoil motif, a 40-amino acid domain that contains 3 conserved disulfides. Trefoil Factors are stable secretory proteins expressed in gastrointestinal mucosa which protect the mucosa from insults, stabilize the mucus layer and affect healing of the epithelium.TFF2 inhibits gastric acid motility & secretion. TFF2 stabilizes glycoproteins in the mucus gel through interactions with carbohydrate side chains. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| The TFF2 protein was lyophilized from 0.4 µm filtered solution at a concentration of 1mg/mL containing 1x PBS pH-7.4. | |
| Stability | |
| Lyophilized TFF2 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution TFF2 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 97.0% as determined by(a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. | |
| Amino acid sequence | |
| EKPSPCQCSR LSPHNRTNCG FPGITSDQCF DNGCCFDSSV TGVPWCFHPL PKQESDQCVM EVSDRRNCGY PGISPEECAS RKCCFSNFIF EVPWCFFPKSVEDCHY. | |
| Biological Activity | |
| Determined by its ability to chemoattract human MCF-7 cells using a concentration 1.0-10.0 ng/ml. | |
| Solubility | |
| It is recommended to reconstitute the lyophilized TFF2 in sterile 18MΩ-cm H2O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. | |
| Precautions | |
| TFF1 Human, His is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P04155 ) | |
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ADMEbio Team
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ADMEbio Team
