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TNF a Rat

Tumor Necrosis Factor-Alpha Rat Recombinant

 
Catalog #
CYK0555
Uniprot Id
P16599
 
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 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
CYK0555-5 7 days 5 µg $120.00
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CYK0555-20 7 days 20 µg $290.00
CYK0555-1 7 days 1 mg $4,320.00
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Product Overview

NameTNF a Rat
Description
Tumor Necrosis Factor-Alpha Rat Recombinant
Accession (Primary)P16599
Synonyms
Tumor Necrosis Factor-alpha, TNF a His, Cachectin, TNF-alpha, Tumor necrosis factor ligand superfamily member 2, TNF-a, N-terminal fragment, NTF, Intracellular domain 1, Intracellular domain 2, ICD2, C-domain 1, C-domain 2, Tumor necrosis factor, soluble form, Tnfa, Tnfsf2, RATTNF, Tnfa.
Introduction
Tumor necrosis factor is a cytokine involved in systemic inflammation and is a member of a group of cytokines that all stimulate the acute phase reaction. TNF is mainly secreted by macrophages. TNF causes apoptotic cell death, cellular proliferation, differentiation, inflammation, tumorigenesis and viral replication, TNF is also involved in lipid metabolism, and coagulation. TNF's primary role is in the regulation of immune cells. Dysregulation and, in particular, overproduction of TNF have been implicated in a variety of human diseases- autoimmune diseases, insulin resistance, and cancer.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered clear solution.
Formulation
TNF a protein solution (1mg/ml) containing Phosphate Buffer Saline (pH7.4), 10% glycerol and 1mM DTT.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
Purity
Greater than 90.0% as determined by analysis by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MGSHM LRSSS QNSSDKPVAH VVANHQAEEQ LEWLSQRANA LLANGMDLKD NQLVVPADGL YLIYSQVLFK GQGCPDYVLL THTVSRFAIS YQEKVSLLSA IKSPCPKDTP EGAELKPWYE PMYLGGVFQL EKGDLLSAEV NLPKYLDITE SGQVYFGVIA L.
Precautions
TNF a Rat is for research use only and not for use in diagnostic or therapeutic procedures.

Target Information: ( P16599 )

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