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TNF b Human

Tumor Necrosis Factor-Beta Human Recombinant

 
Catalog #
CYK0559
Uniprot Id
P01374
 
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 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
CYK0559-5 7 days 5 µg $120.00
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CYK0559-20 7 days 20 µg $290.00
CYK0559-1 7 days 1 mg $4,320.00
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Product Overview

NameTNF b Human
Description
Tumor Necrosis Factor-Beta Human Recombinant
Accession (Primary)P01374
Synonyms
Lymphotoxin-alpha, LT-alpha, TNF-beta, Tumor necrosis factor ligand superfamily member 1, LTA, LT, TNFB, TNFSF1.
Introduction
TNF-b is a potent multifunctional cytokine produced mainly by activated T and B lymphocytes. The protein has been shown to have a specific potent cytotoxic activity on tumor cells and a variety of other target cells as well as being a mediator of inflammation and immune function.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered clear solution.
Formulation
TNF-b protein solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH8.0), 30% glycerol, 0.1M NaCl and 1mM DTT.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
Purity
Greater than 90% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH M LPGVGLTPS AAQTARQHPK MHLAHSTLKP AAHLIGDPSK QNSLLWRANT DRAFLQDGFS LSNNSLLVPT SGIYFVYSQV VFSGKAYSPK ATSSPLYLAH EVQLFSSQYP FHVPLLSSQK MVYPGLQEPW LHSMYHGAAF QLTQGDQLST HTDGIPHLVL SPSTVFFGAF AL.
Biological Activity
Measured in a cytotoxicity assay using L929 mouse fibrosarcoma cells in the presence of the metabolic inhibitor actinomycin D. The ED 50 for this effect is < 0.3 ng/ml.
Precautions
TNF b Human is for research use only and not for use in diagnostic or therapeutic procedures.

Target Information: ( P01374 )

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