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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| CYK0562-2 | 7 days | 2 µg | $120.00 |
Select product before adding to cart
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||
| CYK0562-10 | 7 days | 10 µg | $290.00 | |||
| CYK0562-1 | 7 days | 1 mg | $8,320.00 |
Product Overview | |
| Name | TNFA Bovine |
|---|---|
| Description | |
| Tumor Necrosis Factor-alpha Bovine Recombinant | |
| Accession (Primary) | P01375 |
| Synonyms | |
| Tnfa, Tnfsf2, Cachectin, TNF-alpha, Tumor necrosis factor ligand superfamily member 2. | |
| Introduction | |
| Tumor necrosis factor is a cytokine involved in systemic inflammation and is a member of a group of cytokines that all stimulate the acute phase reaction. TNF is mainly secreted by macrophages. TNF causes apoptotic cell death, cellular proliferation, differentiation, inflammation, tumorigenesis and viral replication, TNF is also involved in lipid metabolism, and coagulation. TNF's primary role is in the regulation of immune cells. Dysregulation and, in particular, overproduction of TNF have been implicated in a variety of human diseases- autoimmune diseases, insulin resistance, and cancer. | |
| Source | |
| Sf9, Baculovirus cells. | |
| Physical Appearance | |
| Sterile filtered colorless solution. | |
| Formulation | |
| TNFA protein solution (1mg/ml) contains Phosphate buffered saline (pH7.4). | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 90.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| LRSSSQNSSD KPVAHVVANH QVEEQLEWLS QRANALLANG MDLKDNQLVV PADGLYLVYS QVLFKGQGCP DYVLLTHTVS RFAISYQEKV NLLSAVKSPC PKDTPEGAEL KPWYEPIYLG GVFQLEKGDQ LSAEVNLPKY LDFAESGQVY FGVIAL HHHH HH | |
| Precautions | |
| TNFA Bovine is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P01375 ) | |
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ADMEbio Team
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ADMEbio Team
