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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| CYK0607-2 | 7 days | 2 µg | $120.00 |
Select product before adding to cart
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| CYK0607-10 | 7 days | 10 µg | $290.00 | |||
| CYK0607-1 | 7 days | 1 mg | $8,320.00 |
Product Overview | |
| Name | TPO Human, His |
|---|---|
| Description | |
| Thrombopoietin Human Recombinant, His Tag | |
| Accession (Primary) | P40225 |
| Synonyms | |
| Megakaryocyte colony-stimulating factor, Myeloproliferative leukemia virus oncogene ligand, C-mpl ligand, ML, Megakaryocyte growth and development factor, MGDF, TPO, MKCSF, MPLLG, MGC163194, THPO. | |
| Introduction | |
| Thrombopoietin is a glycoprotein hormone produced mainly by the liver and the kidneyt hat regulates the production of platelets by the bone marrow. It stimulates the production and differentiation of megakaryocytes, the bone marrow cells that fragment into large numbers of platelets. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| Lyophilized from a concentrated (1mg/ml) solution in water containing no additives. | |
| Stability | |
| Lyophilized Thrombopoietin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution TPO Mouse should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 95.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| SPVAPACDPR LLNKLLRDSH LLHSRLSQCP DVDPLSIPVL LPAVDFSLGE WKTQTEQSKA QDILGAVSLL LEGVMAARGQ LEPSCLSSLL GQLSGQVRLL LGALQGLLGT QLPLQGRTTA HKDPNALFLS LQQLLRGKVR FLLLVEGPTL CVRRTLPTTA VPSSTSQLLT LNKF. | |
| Biological Activity | |
| ED 50 range is less than 0.8ng/ml as determined by the dose dependent stimulation of Mo7e cells. | |
| Solubility | |
| It is recommended to reconstitute the lyophilized Thrombopoietin in sterile 18MΩ-cm H2O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. | |
| Precautions | |
| TPO Human, His is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P40225 ) | |
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ADMEbio Team
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ADMEbio Team
